Question

Please choose from this list to fill in the blanks below. Some choices can be used more than once or not at all.

Choices: rRNA, tRNA, miRNA, mRNA

Typically forms internal base pairs to form a “cloverleaf” structure _________________

The primary transcript is larger than the final, mature form _____________________

Associates with proteins to form the ribosome ________________________

Drosha is needed to process this form of RNA ______________________

Contains protein-coding regions _________________________

This form of RNA contains the largest variety of nucleotide modifications ________________

snoRNAs are used to guide modifications of this form of RNA __________________

May be found within introns of protein-coding RNAs _______________________

Processing involves the snRNAs (U RNAs) ____________________________

Formation of this RNA may involve removal of large and numerous introns __________

Answer 1

1. tRNA or transfer RNA forms cloverleaf structure.

2. The primary transcript of mRNA or messenger RNA is larger but after RNA splicing the mature form becomes shorter.

3. rRNA or ribosomal RNA associates with proteins to form the ribosome.

4. Drosha is needed to process micro RNA or miRNA for the gene regulation.

5. Eukaryotic genes have two regions, Exons and introns. Exon contains protein coding regions.

6. tRNA or transfer RNA contains the largest variety of nucleotide modifications.

7. sno RNA or small nucleolar RNAs are used to guide modifications of other RNAs such as ribosomal RNA or rRNA.

8. Majority of sno RNAs are found inside the introns of protein coding genes.

9. snRNAs (U RNAs) are components of splicesome and required for RNA splicing.

10. Formation of mature messenger RNA from precursor messenger RNA requires removal of large and numerous introns via RNA splicing.