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2. From the list of candidates classify them if they are ligands detected outside or inside of the cell. If you dont know pl
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1.EGF:This is a protein which helps in cell growth and differentiation of different types of cells which binds to receptor,EGFR.It is a mitogenic factor which helps in proliferation of fibroblasts and epithelial cells.It is found inside the body.

2.TESTOSTERONE:It is found inside the body which is produced by testicles in males.It is the male sex hormone which plays a major role in development of sexual organs and secondary characteristicsnlike muscle,bone mass etc.,

3.ACETYLCHOLINE:It is found inside the body of animals and humans.It is a chemical which acts as a neurotransmitter released by nerve cell to regulate other nerve cells,activates pain responses and also in cognitive function.

4.Insulin :It is a hormone which is produced by Beta cells of pancreas inside the body.It controls the metabolism of carbohydrates by promoting the absorption of Glucose(sugar)from carbohydrates in the food.It controls blood sugar levels.

5.Glucagon: It is a hormone found inside the body,produced by Alpha cells of pancreas.It controls the blood glucose levels to drop low.it helps in conversion of stored Glycogen(in liver) to Glucose.

6.Nitric oxide:It is a gas found outside,inhaled in to the body to dilate(widen)blood vessels especially in lungs.It is used to treate respiratory failure.

7.Cortisol:It is a steroidal hormone produced by badrenal gland inside the body.It controls blood sugar levels,reduce inflammation,assist memory inflammation,controls salt and water balance,blood pressure.

8.FGF: Fibroblast growth factor produced inside the body is a growth factor which show active effects on the repair and regeneration of tissues.

9.Epinephrine:(adrtenaline) It is a hormone produced by adrenaline inside the body,it controls emotions such as fear,anger,increase in heart rate,muscle strength.

10.Dopamine:It is a chemical released by catecholamine and phenethylamine produced inside the body,it acts as a hormone and neurotransmitter which plays important role in brain and body.

11.Glutamate:It is a chemical compound released by glutamic acid inside the body where nerve cells used to send signals to other cells.

12.Serotonin :It is a compound which is present in blood platelets and serum,It helps to regulate mood and social behaviour,appetite,digestion,sleep,memory etc.,

13.Estradiol:it is a steroid hormone produced by estrogen inside the body.It is a key female sex hormone which regulates the function of female reproductive system.

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