Question

De Novo lipogenesis ______ directly by the citrate shuttle, which increases the cytosolic levels of _______...

De Novo lipogenesis ______ directly by the citrate shuttle, which increases the cytosolic levels of _______ and _______. The citrate shuttle is "filled" by the anaplerotic carboxylation of pyruvate from the parallel oxidation of ______.

Answer options:

(1) acetyl-CoA (9) glucose
(2) ADP (10) malonyl-CoA
(3) AMP (11) NAD +
(4) ATP (12) NADH
(5) CO2 (13) NADP +
(6) coenzyme A (14) NADPH
(7) FADH2 (15) is inhibited / reduced
(8) fatty acids (16) are stimulated / increased

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Answer #1

Answer :) stimulated; NADPH and acetyl-CoA; Glucose

Lipogenesis is stimulated by the increased cellular levels of NADPH and acetyl-CoA.

Pyruvate production occurs through the oxidation of glucose. It occurs parallel to the citrate shuttle to fulfill the amount of pyruvate.

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