3. Describe the role of vitamins in TCA cycle. How will patients having pyruvate dehydrogenase deficiency...
1) How many CO2 molecules are produced by pyruvate dehydrogenase and the TCA cycle per molecule of glyceraldehydes-3-phosphate that goes through glycolysis, pyruvate dehydrogenase, and the TCA cycle? a.1 b.2 c.3 d.4 e.5 f.6 How many NADPH molecules are produced by pyruvate dehydrogenase and the TCA cycle per molecule of phosphoenolpyruvate that goes through glycolysis, pyruvate dehydrogenase, and the TCA cycle? a.3 b.4 c.6 d.8 e.0
Q4 What is the effect on the tca cycle when muscle mitochondria containing pyruvate dehydrogenase complex is treated with (a) fatty acids or (b) calcium Q5 Why are mutations in citrate synthase very rare?
18. A deficiency in vitamins B6 and B12 could lead to poor clearance of what endogenous metabolite associated with cardiovascular disease? 19. Pyruvate is an alpha-keto acid and is one of the end products of glycolysis. The energy stored in this molecule is used to generate NADH, FADH2, and GTP in the TCA cycle. However, before it gets there, pyruvate must undergo a few metabolic steps in the pyruvate dehydrogenase complex (e.g. oxidative decarboxylation) on its way to becoming acetyl-CoA....
11. Which enzyme is NOT part of the TCA cycle? A. Citrate synthase B. Succinate dehydrogenase C. alpha-ketoglutarate dehydrogenase D. Aconitase E. Pyruvate dehydrogenase
I1. Mammals lack the enzyme a. Lactate dehydrogenase b. Pyruvate kinase Alcohol Dehydrogenase c. d. Pyruvate decarboxylase None of the above are correct e. 12. The first reaction of the Krebs cycle combines Oxaloacetate and Acetyl CoA to make Citrate b. a. Malate and NADH to make Citrate a-ketoglutarate and citrate to make CO2 d. c- Succinate and Citrate to make Oxaloacetate 13. The electrons held by NADH and FADH, are donated to the which complexes in the ETC respectively?...
Describe the role of the malate aspartate shuttle (22.8) in moving cytosolic NADH into the mitochondria and transporting aspartate out of the mitochondria 15: Describe the role of anaerobic glycolysis in the red blood cell 16: Determine the impact of glucagon, insulin, cortisol and epinephrine on the liver, skeletal muscle, and adipose tissue 17: Describe the roles and regulation of citrate synthase, isocitrate dehydrogenase, alpha-ketoglutarate dehydrogenase, and malate dehydrogenase in the TCA cycle 17: Describe the regulation of hexokinase/glucokinase, phosphofructokinase-1...
Write out the reaction catalyzed by the E2 enzymatic component of the pyruvate dehydrogenase complex. Describe the specific role of each cofactor in this reaction.
Question #1: In a mitochondrion, the TCA cycle cannot continue on indefinitely without oxygen because the electron transport chain will be incapable of reducing NADH and FADH2. a.) True b.) False Question #2:How much energy (in the form of ATP) would one get from oxidation of 1 pyruvate molecule if the pH gradient was destroyed in the mitochondrion? a.) 1 ATP b.) 2 ATP c.) 10 ATP d.) 11.5 ATP e.) 12.5 ATP Question #3: The Fe-S clusters in the...
If your student ID number (show)ends in an even number solve 26.2 26.2. Describe in your own words how 2 carbons from pyruvate enter the TCA Cycle (the reactions and intermediates associated with pyruvate dehydrogenase) (25 points)
3 20 The conversion pyruvate to either ethanol or lactate occurs A. when there is an abundance of pyruvate but a deficiency of onygen B. when there is an abundance of BOTH pyruvate and oxygen C. when there is a deficiency of BOTH pyruvate and oxygen D. for the regeneration of NADH so that hydrolysis of ATP can continue to fuel the glycolysis pathway Explain how gluconeogenesis differs from gtycolysis 21 Gluconeogenesis is simply the reverse of all 10 steps...