Question

Select a virus and discuss the following:

o    Disease caused

o    Mode of transmission

o    Virulence factors

o    Diagnostic methods

Answer 1

Answer: HIN ( Human immunodeficiency viruses are species of Lentivirus (it belong to a subgroup of retroviny that infects humans. 1 Disease - caused - HIV, is the visus that causes AIDS ( acquired immune deficiency syndrome). People with HIV are called to have AIDS when they develp certain infections or cancer as the CD4 count is less than 200 → Mode of transmission & - ³ HIV is spread only in certain body fluids (Blood, semen, pre- - seminal fluids, rectal fluids vaginal fluids and breast milk from a person who has HIV.

• virulence factors - " HIV enters through mucous membrane and move to dendritic phagocytes beneath the epithelium, multiplies and is shed (1) HIV virus taken up and amplified by macrophages in sking lymph organs, bone marrow and blood. (III) HIV viny attaches to CD4 and Coreceptors HIV fuses with cell membrane " By the procees of reverse transcriptase Synthesize a DNA copy of RNA. I viral DNA integrated in host Chromosome and can produce a lytic infection of remain Latent. Diagnostic methods - serological methode for detection of antibody Rapid test ELISA and Wester blot & Antigen detection methods P24 antigen Capture test and polymerase chain Reaction or viral load. es religie on latest on