Question

Pick one of the following and discuss:

• Characteristic
• Virulence factor
• Infection caused by specific bacteria. Example: subject – Chap 18: Virulence factors of Staphylococcus aureus.

Answer 1

Virulence factor are the molecules produced by bacteria , fungi and viruses whcih help them in entry and exit to the host cell, suppression of host immune and obtaining nutrition from the host. Virulence factor can spread through horizontal gene transfer and can convert harmless bacteria into dangerous pathogen. The factors like invasins and adhesins used to promote colonization of host organisms. And the factors which give damage to the host includes toxins, hemolysins and proteases.

Staphylococcus aureus produce hyaluronidase which breaks hyaluronic acid the connective tissue component and hemolysins which breaks many cells and red blood cells. It also produce many proteases, lipases and DNases which breaks down proteins, lipids and DNA respectively.

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