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) is a common type of DNA damage that, if not repaired, can lead to the loss of a nucleotide and possibly a shift in the read
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Depurination

Depurination is a kind of mutation that involves loss of pruine bases from the DNA like removal of adenine and/or guanine. Frameshift mutation occurs when a particular nucleotide is removed from the DNA strand. This causes the entire follow up nucleotides to undergo mutation and change the nucleotide rearrangements. Depurination causes removal of the purine and if the damage is not repaired, absence of a purine would cause an error in base pairing and the whole frame of the DNA strand having the mutation will undergo a change.

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