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10) The codon UCA specifies the amino acid serine. a) How many single nucleotide substitutions in...

10) The codon UCA specifies the amino acid serine.

a) How many single nucleotide substitutions in this codon could result in chain termination?

b) How many single nucleotide substitutions in this codon would fail to change the amino acid?

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Answer #1

Answer:

a) 1

There are a total of 64 amino acid combination out of which 3 are stop codons(UGA,UAG,UAA).

Single nucleotide substitution of UCA can either result in UAA (ochre) or UGA (opal) which would immediately result in chain termination.

b) 3 (UCU,UCC and UCG)

UCU, UCC, UCA, UCG, AGU, AGC are the 6 codons that represent the protien serine.

By single nucleotide substitution in UCA we can obtain UCU,UCC and UCG codons that doesnt change the amino acid protien.

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