Question

You have chosen to join WHO. They are particularly interested in your microbiology skills since there have been many outbreaks of disease around the world. Now that you have reviewed your microbiology, you have been notified that you will be sent to one of two areas, West Africa, or the Middle East. In preparation, the Peace Corp would like you to choose one of these areas and complete a plan to deal with outbreaks or potential outbreaks in the area.

Choose an outbreak from those below to investigate.

            Ebola or Middle East respiratory syndrome coronavirus (MERS-CoV)

Locate resources that will provide information about the infection, causing microbe, mode of infection, mode of spread, group or groups specifically susceptible, where outbreak occurred and when, clinical evaluation and diagnosis, infection control.

Find first person reports such as interviews or personal reports or journals on the outbreak. If you need help work with the librarian.

Design and submit an outline of the information you have uncovered. You will use this information to complete the project. The outline should contain information and cited resources for:

1. Name of the disease chosen
2. Causing microbe
3. Mode of infection
4. Mode of spread
5. Group or groups specifically susceptible
6. Where outbreak occurred and when
7. Clinical evaluation and diagnosis
8. Infection control.

Answer 1

Middle East Resperatory Syndrome related Coronavirus (MERS-CoV) MERS is a viral respiratory disease caused by a novel coronavirus that was first Identified in Saudi Arabia in 2012 Cosenaviaus are large family of virus that can cause diseases sainging siom the common cold to severe Acute Respiratory Syndromes (sars), from family coronaviridae. H is a zooncilio virus. They are club-shaped viral spiral peplomer, coloured red. The putin on the surface of the varius that determine höst tropism Forms : SHRS, MERS, SARS-LOVE Transmission: ONen human to human transmission : Dromedary camels are the major neservoir host of MERS-CoV - Shains of MERS-CoV that are identical to human skauns have been isolated from dromedaries in several countries like Oman, Qatar, saudi arabia 2) Human to Human bunsmission: Likely spread from infected person's respuatory sections like through coughing, sheezing! Spiead from ill patients w others through close contact

öymptoms The clinical spectrum of MERS-CoV infection Kanges from no infection of mild respuatory symplom to severe acute hespiratory diseases - A typical presentation is dever, cough & shortness of breath - pneumonia is common finding: Gastrointestirial symptoms include danshoea Diagnosis O Polymerase chain Reaction (PCR) test carried out centers of Diseases Control & Prevention to determine y MERS-CoV infection is actwe do not © Serdlogical testing: a) Blood testing used to check MERS-CoV b) ELISA LIFA_ _) Confirmatory test known as neutralizing antibody arscy. Infection Control O wash hands with water and soop for atleast 20 minute. © Cover mouth & nese with a tissue while coughing or sneezing. $ dispose of the tesute after use Avoid touching nose, eyes, mouth with dirty hands @ Avoid personal contact with infected persons * Cleaning & disinfecting the surface as well as infected objects antibodies

Minimize chance for exposures @ Ensure adherence to standard, contact : aubone precautions O Manage vuitos access $ movement © Implement engineeaing unbols: © Monitor and manage ill and exposed healthcare personnels O Daain e educate healthcare personnels ® Implement environmental infection con bol © Establishing reporting within hospitals and to public health authorities Outbreak . From Het 2014 from 2012 until 31 january 2020, the total number of MERS-CoV infection cases repooled globally to WHO is 2519; with 866 associated deaths In Dec 2019, Wuhan, Hubei province, China became the center of an outbreak of novel wounavaus – Dec 30, 2019 - cluster of cases of prewmonia of unknown ongin sepcoted in China Natwnal Health Commission - Jan 7, 2020 - Novel wronavirus solated - Tan 13,2020 - ist case reposted in Tailand - Jan 19,2020 - 1st case in Korea, Q cases in Beijing - Jan 24, 20.0 - 655 cases reported in China -Jas 11, 2020 - st fatal case de posted Jan 12, 2020 - Named as'ncov-19 / 2019 - Dlov."