Question

Course: EXERCISE 1 MUTATION or in a small group or alone to complete this exercise. In Lab 2. Exercise 8. you determined the amino acid sequence for the following strand of DNA: AGCAATCCGTCTTGG TCGTTAGGCAGA ACC That strand has mutated. It is now obs AGCAACCCGTCTTGG TCGTTGGGCAGA ACC Use your knowledge of mutation and protein synthesis to answer the following questions, delag og hun on 1. What mutation has occurred? Uno de Oromo OY 2. Wil this mutation have a real effect? Why or why not? (Hint: You may want to try Exercise 10 from Lab 2 again, using the mutated DNA strand to make the mutated protein.) boto bo bo o badalo odbora

Answer 1

1. 6th nucleotide has changed from T to C. This will change the second codon from AAT to AAC. Correspondingly, the codon on messenger RNA will change from AAU to AAC. Both of these codons code for the amino acid asparagine.

Because the nucleotides is changed but the amino acid has not changed, this is a type of silent mutation.

2. There will be no effect on the structure and function of protein carrying this mutation. This is because the nucleotide has changed but the amino acid has not changed so the structure will remain the same.

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