Question

Course: EXERCISE 1 BONE REMODELING Work in a small group or alone to complete this exercise 1. Describe one hypothetical situation that illustrates the use it portion of the use it or lose it principle. De- scription of the situation/behavior: Explanation for why more bone is present under these circumstances 2. Describe one hypothetical situation that illustrates the "lose it portion of the use it or lose it principle. De- scription of the situation/behavior: Explanation for why less bone is present under these circumstances:

Answer 1

Answers Bones are formed by a unique class of cells knoon os Osteoclasts. These cells are involved not only in forming new bones, but also in replacing old bone cells with the new and resilient cells. This phenomenon is called resorption, which makes our bones grow and impart strength to our Skelefon system. The "Use it or lose it" principle says that if you use a particular organ, such as brain, muscle or bones ele., they will grow in size and density (for example your muscles grow if you work out of gym) and if you use it less on do not use it at all, you will lose strength in that particular organ. o Let's consider a hypothetical situation for " use it" portion Of "Use it or lose it" principle. A person who works out regular or who exercise regularly have bones with greater density compared to a lazy fellow. Osteoclasts are activated by the positive mechanical pressure triggered by exercise and in response they start to from new bone cells and as a result density of bones increase in a person muolued in regular exercise. Let's consider a hypothetical situation for "lose it" portion of " use it or lose iti principle. Astronauts wook in lack of gravity because of which positive pressure on the bones is reduced and osteoclasts are deactivafed. Puerefore, the bones of astronaufs straf to degenerafe of a great pace and loose bone density

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