Question

6. Can you think of any way that BoNT or TeNT could aid the bacterium that produces it to live a longer and fuller life?

Answer 1

Yes, BoNT or TeNT could aid the bacterium that produces it to live a longer and fuller life.

BoNT- botulinum neurotoxin are produced by anaerobic sporulating bacteria, Clostridium botulinum .

TeNT -tetanus toxin, are produced by anaerobic sporulating bacteria, Clostridium tetani, .

TeNT	BoNT
It is a homogeneous bacterial species	They are divided into several bacterial species and groups
Sporulation period is short	survive during long periods in the sporulating forms
It helps in transportation to central inhibitory interneurons through a retrograde axonal pathway along motor neurons	They target the motor neuron endings or neuromuscular junctions
The dependent inhibition of glycine or GABA exocytosis in inhibitory interneurons results in spastic paralysis	It induces a flaccid paralysis
wound contamination	potent toxin with a long activity duration in neurons