If the cell had high [ATP] and low [AMP], what would you expect to happen to...
If the cell had high [ATP] and low [AMP], what would you expect to happen to the following processes (i.e. process vs. not proceed)? What causes them to process/not proceed and be sure to address any enzymes involved.
Glycolysis
Gluconeogenesis
Glycogen breakdown
Glycogen synthesis
Homework Answers
1.Glycolysis wont proceed
reason : Phosphofructokinase is the rate limiting enzyme in the 3rd step of glycolysis .ATP as as an allosteric inhibitor
2. Gluconeogenesis proceeds
since in the regulation of gluconeogenesis ATP. Act as a promoter
AMP is generally an inhibitor of Fructose-1,6-bisphosphate.since there is low AMP level the reaction proceeds
3.Glycogen breakdown doesnot proceed since the level of AMP which is the allosteric effector of glycogen phosphorylase is low.
4.Glycogen synthesis proceeds the high level of ATP acts as allosteric effector on the glycogen synthase enzyme
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