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. What are the main transcription factors which are downstream of LAT?

. What are the main transcription factors which are downstream of LAT?
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Elf-1 is the main transcription factor for the regulation of LAT gene. The LAT gene codes an adaptor protein (intracellular) that connects the cell surface receptor linkage to the numerous signaling events downstream. It plays an integral role in the cell type functions that express the gene that includes the mast, natural killer and T cells, and the platelets. The Elf-1 expression is very high in the T-cells that include GMCSF cells, interleukin-2 receptor alpha unit and the TCR zeta chain.

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