Elf-1 is the main transcription factor for the regulation of LAT gene. The LAT gene codes an adaptor protein (intracellular) that connects the cell surface receptor linkage to the numerous signaling events downstream. It plays an integral role in the cell type functions that express the gene that includes the mast, natural killer and T cells, and the platelets. The Elf-1 expression is very high in the T-cells that include GMCSF cells, interleukin-2 receptor alpha unit and the TCR zeta chain.
. What are the main transcription factors which are downstream of LAT?
What is the role of the transcription factors? A mutation exists in transcription factors that causes them to bind slightly downstream of the TATA box, causing them to cover the first 3 nucleotides of a gene. RNA polymerase can still transcribe the gene to mRNA, but it misses the first 3 nucleotides. How would this impact translation?
What is the role of the transcription factors? A mutation exists in transcription factors that causes them to bind slightly downstream of the TATA box, causing them to cover the first 3 nucleotides of a gene. RNA polymerase can still transcribe the gene to mRNA, but it misses the first 3 nucleotides. How would this impact translation? RNA is single stranded, and as such, undergoes rapid rates of mutation. How would this affect the ability of siRNAs to combat RNA...
If a protein binds to a DNA sequence downstream of a promoter, transcription is enhanced. Which site is likely to be attached?
6. What are transcription factors and what are the two functional classes of transcription factor? What are the two structural domains of transcription factors? (15 points)
Classify each statement according to whether it applies to general transcription factors only, specific transcription factors only, both, or neither These transcription factors are found in both prokaryotes and eukaryotes. These transcription factors are proteins. These transcription factors form part of the transcription complex. One of these transcription factors binds directly to the TATA box in the core promoter. These transcription factors bind to the operator. These transcription factors bind to enhancer sequences that may be distant from the promoter....
Last week we discussed the role of general transcription factors in forming the transcription initiation complex in eukaryotes. Next week we will look more closely at the regulation of gene expression and the role played by specific transcription factors. Prokaryotes and eukaryotes utilize very different mechanisms for determining which genes are turned on and off and when. In lieu of the prokaryotic operon model, eukaryotes employ a combinatorics approach utilizing both general and specific transcription factors. For this week’s forum,...
QUESTION 12 Which stage of transcription in eukaryotes requires transcription factors? a) initiation b) elongation c) termination d) initiation and elongation e) all of these
QUESTION 12 Which stage of transcription in eukaryotes requires transcription factors? O a) initiation Ob) elongation c) termination d) initiation and elongation e) all of these
Which reaction among transcription factors greatly expands the diversity of regulatory factors that can be generated from a small number of polypeptides? a. Recombination b. Homodimerization c. Heterodimerization d. Trimerizastion
QUESTION 1 Hox genes are genes that code for transcription factors. What do transcription factors do? A. Bind to DNA to make it available for transcription B. Make up specific body parts C. Activate ribosomes QUESTION 2 Genes that need to be turned on at the same time (for example, the genes that encode the proteins that build toes) will all respond to the same transcription factor. A. True B. False QUESTION 3 Hox genes are sometimes called "master switches"....