What is the endogenous ligand for NMDA receptors?
N-methyl-D-aspartate receptor (NMDA) is a glutamate receptor and ion chennel protein occurs in nerve cells. It is an ionotrophic glutamate receptor. When it is activated it allows positively cahrged ions to flow through the cell membrane.
This memebrane recptor is activated when glutamate and glycine are bound to the mebrane.
Alanine aspartic acid, glutamic acid, glycine are the endogenous ligands for this receptor.
what is an example of both exogenous and an endogenous ligand?
What term refers to the pairing of 2 different ligand-bound receptors?
increase intracellular [calcium], how does it affect AMPA receptors? ( we know NMDA promote calcium influx)
Receptors that bind IP3 are generally metabotropic receptors GPCRs receptor tyrosine kinases ligand-gated ion channels
Question 1 (2 points) Which of the following about NMDA receptors is correct? 1) they are voltage gated O2) they are opened by calcium binding 3) glutamate is an antagonist 4) antagonists inhibit excitotoxicity Question 2 (2 points) Saved Ischemia is most likely to cause: O 1) metabolic acidosis with increased respirations 2) metabolic adidosis with decreased respirations 0 3) metabolic alkalosis with increased respirations 4) metabolic alkalosis with decreased respirations
Iontropic/Transmitter Gated Channels- What are the GENERAL characteristics of these channels? Glutamate-Gated Iontropic Receptors: What are these? How do they work? How is NMDA receptor specialized for regulation? How does the NMDA receptor open (steps)?
compare TLRs and NOD-like receptors with respect to cellular location and ligand specificity
Although the ligand-gated ion are ion channels they are considered to be receptors as they only open when bound by which of the following? select two answers please- 1)protein 2)ligands 3)drugs 4)ions 5)sugars
1. Mature B cells require particular receptors to be engaged by ligand to stimulate these cells to become antibody-secreting cells. Fill-in the table below with the receptor(s) on naìˆve B cells that transmit each signal and the corresponding ligand(s) that engage that receptor. (6 pts) Receptor(s) on B cell Ligand(s) Location in body where receptor engagement occurs Signal 1 Signal 2 b. Briefly describe what happens to mature B cells that receive Signal 1, but not Signal 2? (2 pts)...
What are the 3 endogenous catecholamines that are the neurotransmitters in the adrenergic response? What is the main endogenous neurotransmitter that is in cholinergic response?