it can be argued that almost all diseases have have at
their root a cellular basis
Answer: Diseases that occur in the human body are majorly the changes or alterations that affect the individual on its cellular level. For identifying a root of the disease, first, we need to identify the cell types and many other factors that exist within the cell. As it is the key to understanding the underlying cause. As wisely said by (Rudolph Virchow, 1858):
All diseases are disturbances at the cellular level.
There are a number of cell types that can be found in the body, all perform some specific set of functions. Let’s discuss the cell, its related organs, various enzymes that it contains, the regulation of cell, at a genetic level. How all these affect humans for causing issues in their body by the understanding with some examples.
1. The disturbances in the cell types or the problems that occurred by them can cause an effect on the body by causing a disease.
For example:
· Hypertension, which is widely caused by the reason if there is any defect in the junctional complexes present in the epithelial cells of the kidney.
2. The cell consists of various organelles, these organelles also perform their designed set of functions as gifted by nature.
For example:
· Muscular dystrophy, which is mainly caused by the disturbance created by the plasma membrane.
3. There are a number of cell receptors present in the cell that can also become the reason for disease.
For example:
· Cancer, in this certain growth receptors, can be defective that causes a plausible reason for the underlying issue of the body. Although many other reasons are also responsible for various types of cancer that also occur at the root level of the body i.e., cell.
4. Similarly, the enzymes present within these cells may also pose a problem causing disease.
For example:
· Lysosomal storage disease, these are mainly caused by the hydrolytic enzymes in the lysosomes that are meant for transportation when it gets disturbed causes a disease.
5. Various disorders do exist due to genetic level errors which affect humans widely. The genes which are affected occurs within the chromosomes present in the nucleus of the cell.
For example:
· Turner’s syndrome, this is caused when one of the X chromosomes (sex chromosome) is affected, either partially or completely lost in females. Etc.
With the study and elucidation of cell biology that has provided researchers with fundamental insights of knowledge, it has been made possible to understand and develop the diagnosis and treatments respectively. The number of health care providers use tools and techniques like gene sequencing, cytopathological techniques, etc. for diagnosing and further treating the disease that occurs at this i.e. cellular level.
it can be argued that almost all diseases have have at their root a cellular basis
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