All of the following are cofactors used in the reaction catalyzed by pyruvate dehydrogenase EXCEPT ________.
All of the following are cofactors used in the reaction catalyzed by pyruvate dehydrogenase EXCEPT ________.
Biotin |
NAD+ |
FAD |
Thiamine pyrophosphate |
The answer is biotin.
explanation
Thiamine pyrophosphate is required by the enzyme for catalyzing the pyruvate decarboxylation. NAD+ is used for reducing lipoamide. FAD serves as a coenzyme.
hope it helps.
All of the following are cofactors used in the reaction catalyzed by pyruvate dehydrogenase EXCEPT ________....
Vitamins participate in metabolic reactions in their coenzyme forms . Match the following reactions to the respective vitamins or vitamin-derived coenzymes. - decarboxylation reaction in pyruvate dehydrogenase - isocitrate dehydrogenase - reduction reaction in alpha-KG dehydrogenase - succinate dehydrogenase - malate dehydrogenase - pyruvate carboxylase - activation of acyl- or acetyl- moeities A. thiamine pyrophosphate (TPP) B. biotin C. NAD + D. FAD E....
(a) Match a cofactor of pyruvate dehydrogenase with function given in the box. Cofactor A. Coenzyme A (COA-SH) B. NAD C. Thiamine pyrophosphate (TPP) D. FAD E. Lipoamide in oxidized form Functions: Acyl acceptor Electron sink Nucleophile A swinging arm General base ® Oxidizer © Electron conduit Hydrogen atom carrier Reductant (b) Which one of the five steps of the pyruvate dehydrogenase complex reaction is most likely to be metabolically irreversible? Explain.
15. Genetic defect in pyruvate dehydrogenase complex lead a. maple syrup urine disease b. phenyike d. lactic acidemia e. pellagra syrup urine disease b, phenylketonuria c. galactosemia 10. Chemical modification by phosphorylation of pyruvate dehydros a. deactivates the enzyme b. activates the enzyme lation of pyruvate dehydrogenase complex : 17. Pyruvate carboxylase is positively ated through the allosteric mechanism by : a. ATP b. NADH c. Acetyl-SCOA d. TPP e. Biotin 18. Which of the listed coenzymes does not particip...
What is required for the following reaction? CO2 # # O an active site lysine residue thiamine pyrophosphate as a coenzyme a Schiff base as an intermediate NAD as an oxidizing agent biotin as a coenzyme by causing the phosphorylation of Glucagon activates glycolysis. a regulatory enzyme of gluconeogenesis; hexokinase O gluconeogenesis: phosphofructokinase-1 gluconeogenesis, pyruvate kinase glycoslysis: phosphofructokinase-1 O glycoslysis: pyruvate kinase
Write out the reaction catalyzed by the E2 enzymatic component of the pyruvate dehydrogenase complex. Describe the specific role of each cofactor in this reaction.
Question 13 Which of the following cofactors is required for transketolase activity? Thiamine diphosphate Biotin Pyridoxal phosphate NAD+
1. When the cell’s ATP supply is depleted, which of the following enzyme’s activity is increased? Hexokinase Pyruvate kinase Glucokinase Phosphofructokinase Explain why this enzyme activity is tied to ATP levels. 2. The pyruvate kinase catalyzed step is not a reversible reaction in glycolysis, how then does gluconeogenesis start from pyruvate? Show the mechanism of the first step of gluconeogenesis. 3. Which of the following cofactors do not form a covalent bond with enzymes' lysine residues? Lipoamide Biotin NADH Pyridoxyl...
Question 3 40 pts Choose the correct answer from the list. No answer will be used twice. Not all of the answers will be used. provides a flexible linker between active sites within the pyruvate dehydrogenase (PDH) complex. [Choose] acetyl COA pyruvate dehydrogenase lipoamide thiamine pyrophosphate FAD endoplasmic reticulum mitochondria The coenzyme is the prosthetic group in the decarboxylation of pyruvate. [Choose ] is a large, multi-subunit enzyme complex that links glycolysis and the citric acid cycle under aerobic conditions....
Question 3 40 pts Choose the correct answer from the list. No answer will be used twice. Not all of the answers will be used. provides a flexible linker between active sites within the pyruvate dehydrogenase (PDH) complex. [Choose acetyl COA pyruvate dehydrogenase lipoamide thiamine pyrophosphate FAD endoplasmic reticulum mitochondria The coenzyme is the prosthetic group in the decarboxylation of pyruvate. [Choose] is a large, multi-subunit enzyme complex that links glycolysis and the citric acid cycle under aerobic conditions. Where...
FAD lipoamide dihydrolipoyl dehydrogenase (E3) pyruvate dehydrogenase (EI) FADH, NAD dihydrolipoyl transacetylase (E2) >NADH + H HOC CH CH3-C- > CH3-C-s pyruvate CH3-C-COA acetyl-CoA COA