Question

4. The protein shown below is an enzyme-linked receptor. This means that this protein... Circle your answer a) can speed up chemical reactions. b) can bind to certain signaling molecules. c) all of the above. D. Think about the enzyme-linked receptor we discussed in class. After the signaling molecules binds to this receptor, it causes the active site on the receptor to become available. What binds to this active site? E. Consider the molecule you named in the previous question. This molecule causes the enzyme-linked receptor to become (phosphorylated or de-phosphorylated). F. Think about the action you identified in the previous question. After this occurs, it allows proteins to bind to the enzyme-linked receptor. What are these proteins called, and what do these proteins do? G. After bridging proteins bind to the Ras protein, it causes Ras to release a molecule of molecule is then replaced by_ . The released H. When Ras has ( GDP or GTP) attached to it, Ras can trigger the (phosphorylation or dephosphorylation of other proteins. 1. Once Ras is activated, it can...circle your answer a) phosphorylate a large number/variety of other proteins, all at once. b) phosphorylate one protein, which then phosphorylates another protein, which then phosphorylates another protein, etc. J. Of all of the questions from this assignment which one gave you the most trouble?

Answer 1

4. c) All of the above

  An enzyme-linked receptor, also known as a catalytic receptor,is transmembrane receptor, where the binding of an extracellular ligand causes enzymatic activity on the intracellular side. Hence a catalytic receptor is an integral membrane protein possessing both enzymatic catalytic and receptor functions.

D)  An enzyme-linked receptor, also known as a catalytic receptor, is a transmembrane receptor, where the binding of an extracellular ligand causes enzymatic activity on the intracellular side. Hence a catalytic receptor is an integral membrane protein possessing both enzymatic catalytic and receptor functions.

They have two important domains, an extra-cellular ligand binding domain and an intracellular domain, which has a catalytic function; and a single transmembrane helix. The signaling molecule binds to the receptor on the outside of the cell and causes a conformational change on the catalytic function located on the receptor inside the cell.

E) The enzyme linked receptor become phosphorylated.

F) After Phosphorylation occurs, the proteins are binds to the receptor. Which are called ligands which makes confirmational changes in the receptor leads to the formation of active site.

H) GDP and Phosphorylation

I) a) Phosphorylates a large number or variety of protein all at once.