Question

Extra Credit: As we will see next week, aromatic compounds react well with electrophiles at their most electron rich centers and more electron-rich aromatics are more reactive. Compared to benzene, do you think pyridine (drawn below) is more or less reactive. Why? Also, where do you think that pyridine will react with an electrophile. (4 pts)

Answer 1

Ang :- 1) weak aromatic compound react well with electrophile at their electron rich centres. More eig 4 + E [5 я protonated Jone pair present on mitrogen of Pyrode makes it move aromatic it reacts with electrophile because of stability of proton intermediate as shown above. 2) mose election rich aromatics are more reactive as compared to benzene because of presence of lone pór which push up towards electrophile. e.g. pyooole furan 1 1 H 3) Pyridine is less seactive than Pyroole & benzene also becouse - Pyridine is more stable in it's unseacted state as compare to pyssole due to it's aromatic noture. P + E As we [Not possible] Rean not happened. See ppoole [9 -point] it is stable than pyndine all this reasons Pyridine not react with electrophie it is unstable if it react with electoophile. as shown above Due to