Question

Provide an explanation for why cancer cells often have a “stable” but “altered” karyotype.

Answer 1

The genetic level change observed in a cancer cell is “mutation”.Mutation is the underlying cause of cancer.The mutation that happened in a cell's karyotype will mainly cause the defective cell to multiplay uncontrollably.This uncontrolled multiplication causes the formation of mass or metastasis.The cancer cells often have a “stable” but “altered” genetic information.The mutation will result “altered” karyotype compare with normal cell in a cancer patient and also will be “stable” as the mutant cell undergoes uncontrolled cell division from the parent mutant cell.So all the progeny cells arised from that mutant cell will have “stable” and same karyotype.