A silent mutation leads to the decreased amount of protein products. Why does this happen?
A silent mutation leads to the decreased amount of protein products. Why does this happen?
Homework Answers
Silent mutation is the change in a nucleotide base which results in amino acid is not altered in the encoded protein. Usually the protein expression is not affected, but may be reduced or increased in some cases based on the availability of charged t-RNA (containing amino acid being coded by the mutated codon). Different organisms may have different set of codon adaptation. Some codons may be preferred while some may not based on the t-RNA pool.
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A silent mutation leads to the decreased amount of protein
products. Why does this happen?
A silent mutation would cause: O A change in the conformation of a protein The inhibition...
A silent mutation would cause: O A change in the conformation of a protein The inhibition of transcription 0 The inhibition of translation No change in the amino acid sequence of a protein
A silent mutation is one that does not affect polypeptide structure. Write a code for an...
A silent mutation is one that does not affect polypeptide structure. Write a code for an original DNA strand containing 12 bases, and then mutate the original DNA so that the final polypeptide is unaffected. Circle the mutation. Original DNA Mutated DNA polypeptide sequence >
1. In a "silent" mutation A) The codon that mutates does not cause a change in...
1. In a "silent" mutation A) The codon that mutates does not cause a change in the amino acid specified B) The codon that mutates causes change in the amino acid specified C) The codon that mutates cause a stop codon to occur instead of the placement of an amino acid D) The mutation does not occur in a codon E) The mutation is not in DNA 2. In a "nonsense" mutation A) The codon that mutates does not cause...
Which of the following adenines could you mutate to create a silent transversion mutation? 5'-ATG GGA...
Which of the following adenines could you mutate to create a silent transversion mutation? 5'-ATG GGA TGG CAC CTG-3' Answer: A to G or C to T -I don't really understand why this is the answer. I get that the adenine you will use is the one in the GGA, since it is the third codon it will cause a silent mutation. But why does the answer key say A to G or C to T? Shouldn't it say A...
Kidney damage leads to protein in the urine. The amount of protein in the urine is...
Kidney damage leads to protein in the urine. The amount of protein in the urine is directly related to the severity of kidney damage. Design a lab procedure for determining the amount of protein in a urine sample. Keep in mind that the maximum absorbance may not be 540nm due to interference created by the other components in a sample of urine.
What would you expect to happen to a newly synthesized soluble protein if a mutation caused...
What would you expect to happen to a newly synthesized soluble protein if a mutation caused the deletion of the KDEL sequence? a. The protein would be returned to the ER in COPI-coated vesicles. b. The protein will be carried forward through the Golgi apparatus. c. The protein will be trapped in COPII vesicles . d. The protein will be incorporated into COPI vesicles. e. The protein will be recognized by KDEL receptors and a retrieval sequence (KDEL sequence) will...
A mutation in the gene for a particular protein gives rise to the disease osteogenesis imperfecta....
A mutation in the gene for a particular protein gives rise to the disease osteogenesis imperfecta. Answer (and explain) the following five questions in one sentence each. What is the name of the protein? What is the mutation in this protein? Describe the structure of this protein. Why does this mutation disrupt the structure of the protein? Will taking extra Vitamin C help cure osteogeneis imperfect? Why or why not?
Please explain why,, for the second prob, why is it not missense mutation.. 20. The following...
Please explain why,,
for the second prob, why is it not missense mutation..
20. The following bit of the human RefSeq includes the entire first exon of a protein coding gene and part of the second exon 5'-AACTAACCACTGTCCGTACTCTGCCAGCCATCCGTAGC-3' 21. The canonical splice junctions are 5'-GU....AG-3', where ... indicates additional intronic sequence. Which of the following is a candidate for the protein-coding portion of the processed mRNA from this sequence? a. 5'-TACCGACCGTCTACCAATAAC-3' b. 5'-GCTACGGATGGCTGGCAGAGT-3' c. 5' -GUACGGACAGUGGUUAGUUCC-3' d. 5'-AUGGCUGGCAGAUGGUUAGUU-3' e. 5'-AACTAACCATCTGCCAGCCAT-3'...
what is a mutation and why mutations can affect protein structure and function. Be very specific.
what is a mutation and why mutations can affect protein structure and function. Be very specific.
Question 26 (4 points) Bonus question: The CFTR protein is found in the plasma membrane of...
Question 26 (4 points) Bonus question: The CFTR protein is found in the plasma membrane of individuals unaffected with cystic fibrosis. A common mutation in CFTR causes the protein to be trapped in the ER and eventually degraded. Why does this happen?
A silent mutation would cause: O A change in the conformation of a protein The inhibition of transcription 0 The inhibition of translation No change in the amino acid sequence of a protein
A silent mutation is one that does not affect polypeptide structure. Write a code for an original DNA strand containing 12 bases, and then mutate the original DNA so that the final polypeptide is unaffected. Circle the mutation. Original DNA Mutated DNA polypeptide sequence >
Please explain why,,
for the second prob, why is it not missense mutation..
20. The following bit of the human RefSeq includes the entire first exon of a protein coding gene and part of the second exon 5'-AACTAACCACTGTCCGTACTCTGCCAGCCATCCGTAGC-3' 21. The canonical splice junctions are 5'-GU....AG-3', where ... indicates additional intronic sequence. Which of the following is a candidate for the protein-coding portion of the processed mRNA from this sequence? a. 5'-TACCGACCGTCTACCAATAAC-3' b. 5'-GCTACGGATGGCTGGCAGAGT-3' c. 5' -GUACGGACAGUGGUUAGUUCC-3' d. 5'-AUGGCUGGCAGAUGGUUAGUU-3' e. 5'-AACTAACCATCTGCCAGCCAT-3'...
Question 26 (4 points) Bonus question: The CFTR protein is found in the plasma membrane of individuals unaffected with cystic fibrosis. A common mutation in CFTR causes the protein to be trapped in the ER and eventually degraded. Why does this happen?
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