Question

Compare and contrast active site and allosteric sites. How does each affect metabolism?

Answer 1

During the enzyme catalyzed reaction after the substrate is added the substrate is added a specific pocket of enzyme which is known as the active site of the enzyme. But regarding the enzyme activity there are also some places except the active site where the enzyme activator or inhibitor can bind the change the conformation of enzyme active site which is known as allosteric site.

During the time of metabolism the substrate always binds with the active site of the enzyme and the reaction proceeds. But there are also some compounds which are known as enzyme activator or inhibitor. They bind in the allosteric site of the enzyme and changes the conformation of the active site and also modulate the binding of more substrate and hence also the rate of the biochemical reaction.,