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What is the primary reason that only a single reading frame is used during translation of...

What is the primary reason that only a single reading frame is used during translation of a given monocistronic mRNA.
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Monocistronic messenger RNA is the one which carries only one gene in it. Therefore during the process of translation, it uses only single reading frame so that it gives rise to single peptide sequence. If multiple reading frames will be used, then multiple peptide sequences will be formed and this occurs in polycistronic messenger RNA.

(Monocistronic messenger RNA carries single gene where polycistronic carries multiple genes. The former is present in eukaryotes and the latter is present in prokaryotes).

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