Question

Racin inhibits protein synthesis by targeting which of the following steps during translation? a. depurination of...

Racin inhibits protein synthesis by targeting which of the following steps during translation?

a. depurination of 28S rRNA

b. translation termination

c. translation initiation

d. ribosome translocation

e. binding the mRNA to the ribosome

Please give reasoning behind answer. Thanks

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Answer #1

Ricin is extracted from castor plant (Ricinus communis) it inhibits the protein synthesis mechanism by irreversibly degrading the ribosomes; making ribosomes unavailable for protein synthesis. It specifically hydrolysis the glycosidic bond in the larger subunit of the ribosome, namely 28s rRNA; which completely degrades or breakdown ribosomes. This leads to incomplete protein synthesis.

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