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Looking at congenital heart defects, what is the probability of this being passed down to offspring?...

Looking at congenital heart defects, what is the probability of this being passed down to offspring?

a) if both patents have a heart defect, what is the punnet square, genotype and phenotype?
b) If one parent has the heart defect, what is the punnet square, genotype and phenotype? (the second parent does not have the defect and is not a carrier)
c) If one parent has the heart defect, what is the punnet square, genotype and phenotype? (the second parent does not have the defect but IS a carrier of the gene)

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Answer #1

A congenital heart defect is heart problem that the baby has at birth. In most cases there is no clear cause for the heart defect. It is a combination of the genetic and environmental factors. About 1% of children are born with a congenital Heart Disease. There is a 3 times risk of CHD when a first degree relation has the defect.

Some heart defects have autosmal dominant inheritance which means that a parent with defect has 50% chance to have a baby with the same defect. Males and females are equally affected. There is 50% chance that the child wont be affected in such a case.

Familial congenital CHD can inherit as autosomal dominant , recessive , and X linked . I m providing informatiom about all the type of inheritance along with this.

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