Question

Please help me on my Medicinal Chemistry paper

Please answer my question with more explanations and based on medicinal chemistry concept. Also. Please type the answer. Thanks

The topic of my paper is

“Medicinal Chemistry Approaches for the Treatment and Prevention of Alzheimer’s disease”

1. Is it age related diseases? If yes who is more affecting? And why?
2. Which part of the world (continent) more common and affecting by this disease?
3. Is hygiene care make a difference if yes how?
4. How to reduce the risk of Alzheimer’s disease?
5. Is there any vaccine, drug or any other effective treatment to control the spreading of this disease?
6. Is this genetic disorder disease (genetically transferred)
7. Is it contagious diseases?

Answer 1

1.. The greatest known risk factor is increasing age, and the majority of people with Alzheimer's are 65 and older. But Alzheimer's is not just a disease of old age. Approximately 200,000 Americans under the age of 65 have younger-onset Alzheimer's disease (also known as early-onset Alzheimer's).

2.. The top ten countries who are most affected by Alzheimer's include (in the correct order of highest rate): Finland, United States, Canada, Iceland, Sweden, Switzerland, Norway, Denmark, Netherlands, and Belgium. Those with the lowest rates include India, Cambodia, Georgia, and Singapore.

3.. yes hygeine care make a difference Wine rounds out the list of of 10 "brain healthy" food groups that help protect against Alzheimer's: green leafy vegetables, other vegetables, nuts, berries, beans, whole grains, fish, poultry, olive oil and wine.

4...Evidence suggests that the DHA found in these healthy fats may help prevent Alzheimer's disease and dementia by reducing beta-amyloid plaques. Food sources include cold-water fish such as salmon, tuna, trout, mackerel, seaweed, and sardines.

The U.S. Food and Drug Administration (FDA) has approved two types of medications — cholinesterase inhibitors (Aricept®, Exelon®, Razadyne®) and memantine (Namenda®) — to treat the cognitive symptoms (memory loss, confusion, and problems with thinking and reasoning) of Alzheimer's disease.

Food groups that help protect against Alzheimer's: green leafy vegetables, other vegetables, nuts, berries, beans, whole grains, fish, poultry, olive oil and wine.  

5.. Genetic mutation—A permanent change in a gene that can be passed on to children. The rare, early-onset familial form of Alzheimer's disease is associated with mutations in genes on chromosomes 21, 14, and 1. Genetic risk factor—A change in a gene that increases a person's risk of developing a disease.

6.. NO Alzheimer disease is not a contanious disease because a contagious disease is a subset category of transmissible diseases, which are transmitted to other persons, either by physical contact with the person suffering the disease, or by casual contact with their secretions or objects touched by them or airborne route among other routes.