Citric acid cycle also known as tricorboxylic acid cycle (TCA) or Krebs cycle is the important pathway of cellular respiration. It uses acetyl CO A released out of oxidation of pyruvate as a starting compound to produce ATP or energy by series of redox reactions.
In the second step citrate is coming converted to isocitrate by removal and addition of H20. In step 3 Isocitrate is the substrate for isocitrate dehydrogenase which oxidises isocitrate and release C02 and alpha keto glutarate which is a five carbon compound. Since isocitrate dehydrogenase make use of isocitrate only, Aconitase in step 2 interconvert citrate to isocitrate creating the setup for step 3.
Explain how step 2 of the Citric acid cycle acts as a setup reaction for the...
6. Citric Acid Cycle Draw the complete Citric Acid Cycle pathway, include: (a) Total number of steps in Citric Acid Cycle? (b) Specify the type of reaction in each step? (c) Name the enzymes in each step? (d) How many redox reactions are present in Citric Acid Cycle?
Part B Use the structures given in the cycle shown before this part identify the enzymes involved in each step of the citric acid cycle by completing each sentence Match the words in the left column to the appropriate blanks in the sentences on the right. View Available Hint(s) Reset Help isocitrate dehydrogenase aconitase citrate synthase fumarate hydratase succinate dehydrogenase succinyl-CoA synthetase a-ketoglutarate dehydrogenase malate dehydrogenase In step 1, oxaloacetate condenses with acetyl-CoA to form citrate, which is catalyzed by...
1. What are the products of one turn of the citric acid cycle (do not consider oxidative phosphorylation during electron transport? 2. In step 3 of the citric acid cycle, isocitrate is converted into a-ketoglutarate. What is/are other product(s) of this reaction? 3. NADH is produced during glycolysis in the cytosol. How does it enter the mitochondria for further oxidation? 4. What is the total number of ATP molecules produced from the myristic acid CH3(CH12)COOH found in coconut oil? 5....
Be able to label any and all steps in: glycolysis, the citric acid cycle and oxidative phosphorylation. Including (but not limited to): names of compounds, enzymes (for extra credit where stated), ATP produced, NADH and FADH2 produced, and the role or importance of main molecules. **Note: this is really three questions in one. Therefore, know how to label the sequences in 1. Glycolysis 2. The citric acid cycle and 3. Oxidative phosphorylation .
1. The enzyme responsible for the substrate level phosphorylation in the citric acid cycle is: a succinate dehydrogenase b. a-ketoglutarate dehydrogenase c. succinyl thiokinase d. isocitrate dehydrogenase e. aconitase 2. Which of the listed enzymes of the TCA cycle does not represent a regulatory enzyme?: a. isocitrate dehydrogenase b. succinate dehydrogenase c. malate dehydrogenase d. a-ketoglutarate dehydrogenase complex e. citrate synthase 3. Oxidative decarboxylation of pyruvic acid is regulated by: a. cyclic AMP-dependent mechanism b. cyclic AMP-independent mechanism 4. The...
1. Select the TRUE statement about the citric acid cycle. A. Isocitrate dehydrogenase is a multienzyme complex that is very similar to the pyruvate dehydrogenase complex B. The two decarboxylation steps occur right after each other, first via oxidative alpha- decarboxylation, then via oxidative beta- decarboxylation. C. In one turn of the cycle, the two carbons that enter the cycle as acetyl CoA are the same two carbons that are released as CO2. D. A flavin containing dehydrogenase enzymes oxidizes...
6. (10 pts) For the following step in the citric acid cycle, COO H COO CH Succinate dehydrogenase + FAD + FADH CH, OOC H COO Succinate Fumarate a. What class of enzyme catalyzes this reaction? b. How does this step ultimately contribute to the formation of ATP? Be specific, c. Knowing that the next step is a hydration of the alkene, briefly explain why this step needed to occur? That is, why not hydrate the succinate?
Question 6
6. (10 pts) For the following step in the citric acid cycle, COO H COO CH Succinate dehydrogenase + FAD + FADH CH, OOC H COO Succinate Fumarate a. What class of enzyme catalyzes this reaction? b. How does this step ultimately contribute to the formation of ATP? Be specific, c. Knowing that the next step is a hydration of the alkene, briefly explain why this step needed to occur? That is, why not hydrate the succinate?
2) Write a balanced equation for each the following pathways a) Lactate Fermentation b) Ethanol fermentation c) Oxidative decarboxylation in citric acid cycle d) Oxidative decarboxylation in glucose metabolism other than citric acid cycle
why is step 8 (dehydrogenation) of the citric acid cycle regulated? in other words why is malate dehydrogenase regulated? plz explain with detalis and give me a definite answer why that step is being regulated