1. What is the source and category of antigen displayed by MHC Class I?
2. What is the source and category of antigen displayed by MHC Class II?
3. Which cell that is part of the innate defenses destroys cells lacking our own MHC-I?
1. What is the source and category of antigen displayed by MHC Class I? 2. What...
The immune system is self-restricted and the self-restriction is seen with immunological responses that involve both the MHC class I and the MHC class II molecules. Define MHC class I and class II restriction, which molecules and cells are involved and which stage of the immune response (stages 1 – 8 in figure 1-7) the class I and class II restriction occurs (pick a stage from figure 1-7, state that stage, and describe the MHC restriction taking place (class I...
Handout IG2-2 Class I MHC-Peptide Interactions Place the steps of the antigen-processing pathway for endogenous antigen in the correct order Alpha chain of class I MHC binds peptide. Endogenous antigen within cytosol is degraded by proteasome. Peptides are transported into endoplasmic reticulum by TAP Alpha chain of class I MHC binds β2-microglobulin. Peptide-class I MHC is transported to Golgj complex and then to cell surface. Class I MHC peptide binds to CD8+T cell.
Immunology The immune system is self-restricted and the self-restriction is seen with immunological responses that involve both the MHC class I and the MHC class II molecules. Define MHC class I and class II restriction, which molecules and cells are involved and which stage of the immune response (stages 1 – 8 in figure 1-7 on page 20) the class I and class II restriction occurs (pick a stage from figure 1-7, state that stage, and describe the MHC restriction...
3 pts Question 12 What type(s) of MHC molecules are present on antigen-presenting cells? Neither MHC I nor MHC II O Both MHC I and MHC II MHC I only OM ll only Question 13 3 pts A B-cell may be activated by: A cytotoxic T-cell A natural killer T-cell Another B-cell A TFH cell
1 pts T cytotoxic cell activation involves: O antigen binding to antibody on B cells O T cell receptor (TCR) binding to antigen displayed in MHC-II O T cell receptor (TCR) binding to antigen displayed in MHC- natural killer cells 1 pts Question 13 Question 11 1 pts Which of the following is found on the surface of T cells! O All of these O MHC-II O CD and TCR TCR O CD 1 pts Question 12 Question 10 1...
Which of the following is incorrectly matched? MHC-II ; alpha 1,2 and beta 1,2 domains MHC-II ; present on all body cells MHC-I ; antigen binding site is composed of alpha 1 and alpha 2 domains MHC-II ; presents extracellular antigens from pathogens or other non-self proteins MHC-I ; presents intracellular antigens from viruses or degraded self-proteins MHC-I ; presents antigen to cytotoxic T cells MHC-I ; alpha 1,2,3 domains and beta macroglobulin MHC-II ; presents antigen to T helper cells...
Which of the following statements about how B and T cells recognize antigen are true? Correct any false statements. a. B cells only recognize antigen presented by class I or class II MHC molecules. b. Both cell types can recognize extra-cellular antigen free-floating in solution. c. Both cell types recognize extracellular matrix-bound antigens. d. T cells only recognize antigen presented by class I or class II MHC molecules.
What determines whether a dendritic cell or a macrophage presents the antigen? Which one has MHC I and MHC II receptors
The transporter in antigen processing genes encode subunits of a heterodimer pump that transports peptides from the cytosol into the endoplasmic reticulum, where they can associate with newly translated Class la chains O B-2 microglobulin. Proteosomes. Immunoglobulin molecules. Class Il a and B chains. Question 20 5 pts Soluble proteins are examples of: Bone marrow dependent antigens. Bone marrow independent antigens., Thymus dependent antigens. Thymus independent antigens. Good food. The features of bound peptide fragments isolated from different class molecules...
Question 13 3 pt: MHC I and MHC Il differ from each other in that: MHC I, but not MHC II, is necessary for T cells to kill cells presenting endogenous antigen MHC I, but not MHC II, primarily present exogenous antigens to CD8+ T cells MHC I, but not MHC II, is necessary for T cells to activate B cells MHC II, but not MHC I, primarily present endogenous antigens to CD4+ T cells Question 14 3 pts In...