MTHFD1 is a genetic variant that may increase the dietary requirement for choline, how?
This enzyme produces biogically active folate which can produced many cell division and many other function.
Variants of this MTHFD 1 gene produces a phenotype enzyme which produced huge folate and thus it has necessitates of more choline as choline and folate function similarly partly.
Homocysteine is an Amino acids which is a risk factor associated with cardiovascular disease.
Choline and folate are both essential in detoxifying the homocysteine and also in the case of s- adenosyl methionine formation which is used in methylation reaction that why if folate is being converted then the choline is needed very much.
Thank you
MTHFD1 is a genetic variant that may increase the dietary requirement for choline, how?
Identify 2 genetic variants that may increase the dietary requirement for choline?
Explain the difference between the concept of the traditional use of the word “genetic mutation” and the more contemporary term “genetic variant”. Explain the concepts of 1) harmful mutations and purifying selection, 2) of neutral mutations and 3) variants that are retained via positive (or Darwinian) selection. Explain how a positive variant may influence local alleles (on the same chromosome very close to the new positive variant) by selective sweep of hitchhiker alleles.
Which of the following factors may, in different situations, either increase or decrease genetic variation in a population? natural selection gene flow non-random mating genetic drift stabilizing selection
What do the structures of Phosphatidyl Choline and a Triacylglycerol have in common? How do the structures of these two types of lipids differ?
4. If Mr. Smith has a genetic risk for
hypertension, in what other ways may this information be used to
inform the management of his disease?
Frank Smith: Application Mr. Smith has a prior history of hypertension for which he does not currently have the necessary prescriptions. A nursing assessment needs to include dietary considerations along with questions about the availability of his healthcare provider and financial status. His racial/ethnicity status should also be determined to evaluate for the presence...
Apart from genetic factors, research has shown that lifestyle behaviors, dietary, environmental factors and occupational exposure contribute to the number of heart disease cases and deaths. Discuss the difference between modifiable and non-modifiable risk factors and give 3 examples of each.
Apart from genetic factors, research has shown that lifestyle behaviors, dietary, environmental factors and occupational exposure contribute to the number of heart disease cases and deaths. Discuss the difference between modifiable and non-modifiable risk factors and give 3 examples of each.
How might choline deficiency be contributing to the fatty liver and liver dysfunction? Propose two mechanisms based on the physiological functions of this nutrient.
Question 36 2 pts How does the sexual life cycle increase the genetic variation in a species? by allowing crossing over by conserving chromosomal gene order by increasing gene stability by allowing fertilization
Within populations Between populations Increase genetic variation Decrease genetic variation Answer Bank migration genetic drift mutation some types of natural selection