Why have the centromeric regions of the human genome been difficult to sequence? What surprising discovery was made when the centromeric region of Arabidopsiswas first sequenced?
The centomere region is responsible for linking the pair of sister chromatids. The centomeric region is difficult to sequence because it contain mainly short repetitive DNA that is difficult to sequence and also the variation within these repetitive DNA that is mainly alpha satellite DNA is highly variable between humans . These two reasons make difficult to sequence the centomeric region of human genome.
The suprisingly discovery that was made while sequencing of centomeric region of arabidopsis is that centomere region of arabidopsis is very similar to the human centomere. The variation of repeats is also very similar between human and arabidosis are similar.
Why have the centromeric regions of the human genome been difficult to sequence? What surprising discovery...
a) Why was it important to sequence ESTs as well as the human genome? A. Because ESTs contain sequence that is not in the genome B. To identify the location of the exons C. To identify the location of the promoter D. Because ESTs are different than what is in the human genome b) What regions of the genome are missing if only ESTs are sequenced? A. cDNA B. Exons C. mRNA D. 3'UTR E. Introns c) Name a region...
. What is the meaning of the term consensus sequence? Why would a scientist search the human genome to find different locations where a particular consensus sequences is found?
Question 4 Part A [10 marks] A human genome has been re-sequenced using a sequencing technology that produces 100 bp reads of high quality data. The DNA was sheared to make a paired-end library with a size range of 1500 bp +- 500 bp and sequenced to generate paired-end reads. The analysis pipeline takes short-read sequence data and aligns it to a repeat-masked version of the reference human genome sequence assembly using BLASTN. This table summarizes the results from three...
The human genome contains a family genes that code for
different forms of myosin, which are expressed in different cell
types and hav somewhat different functionsWhere the sequence of
each gene would you expect to see differences among them?
Done Chapter 14 Homework Assignment The human genome contains a family of genes that code for different forms of myosin, which are expressed in different cell types and have somewhat different functions. Where in the sequence of each gene would you...
Below is shown an 8kb region of the human genome, with the
proportion of the nucleotides that are identical between the human
sequence and the homologous sequence from mouse on the top graph,
and the location of sequences mapped from an RNA-sequencing
experiment on the bottom graph
What region is likely to be an
enhancer element upstream of the promoter?
What region is likely to be an enhancer element in an
intron?
100 % conservation RNA-seq 2000 4000 6000 8000...
Write true or false ______ 1. The DNA sequence of one human being is on average 99.9% identical to another random human being. ______ 2. As of 2009, all living human beings have had their entire genome sequenced. ______ 3. The nucleotide bases present in a DNA sequence are A, U, G, C. ______ 4. Techniques that enabled scientists to clone genes were developed in the 1970s. ______ 5. A restriction enzyme is useful because it is a generic enzyme...
1) What is the ultimate goal of the Human Genome Project? A) to rid the human population of genetic disease B) to better understand the genes and regulatory elements of the genome C) to map all the genes in the genome so they can be edited with CRISPR-cas D) to understand all of the proteins generated in a cell 2) ________ alleles are those that are not epistatic over nonallelic genes that influence the same phenotypic characteristic. A) Additive B)...
(Molecular Biology) What specifically is coding DNA? Only roughly 2% of the human genome is made up of coding gene sequence. Briefly describe 4 types of the non-coding other 98% of DNA
You have been given a 1.0 kbp human genome fragment that does not contain any repeated sequences. Your plan is to use it as a probe for a Southern Blot containing your friend's genomic DNA. You prepare your gel by digesting with the following restriction enzymes in the following lanes: Lane 1: size marker Lane 2: EcoRI Lane 3: HindIII Lane 4: BamHI Your friend happens to be homozygous for the region you are probing. Does that mean you will...
You have discovered a new gene in the human genome! You sequence the cDNA, and find the COS You determine that the lensthof the CDS is 650 nucleotides this includes the start codon and the stop codon). How many amino acids are present in the peptide that is translated from your sene HTML Ed BIVA-A-I EE 3 a XXE - EP 22 NV V VOTT12pt - Paragraph р 2 pts Question 3 wou need to add to your 100 microliter...