Question

describe the pathology of cellulitis at a cellular level

Answer 1

Ans) Cellulitis is a bacterial skin and soft tissue infection which occurs when the physical skin barrier, the immune system and/or the circulatory system are impaired. Diabetes, obesity and old age are associated with defects in all of these areas and as a result are major predisposing factors for cellulitis.

- A break in skin integrity almost always precedes infection.
As the offending organism invades the compromised area, it overwhelms the defensive cells, including the neutrophils, eosinophils, basophils, and mast cells, that normally contain and localize the inflammation.
As cellulitis progresses, the organism invades tissue around the initial wound site.