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9. Approximately how many generations would it take to change the frequency of an allele from 1.0 to 0.80 if the mutation rat

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Ans.9) Let an allele denoted by "A" is being mutated to "B" at a rate (r = 1 x 10-5) .

If "pi" is the allelic frequency at given time and "pi = 1" so with the mutation rate (r = 1 x 10-5) the frequency "p" after first generation changes to

pi - pi+1 = 1 - 1x 10-5 = 0.9999

So, \Deltap = pi - pi-1 = 1 - n(1 x 10-5) = 0.80

By calculating n = 20,000

So it will take 20,000 generation to change from p=1 to p=0.8

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