In a theoretical operon, genes A, B, C, and D represent the repressor gene, the promoter sequence, the operator gene, and the structural gene, but not necessarily in the order named. This operon is concerned with the metabolism of a theoretical molecule (tm). From the data provided in the accompanying table, first decide whether the operon is inducible or repressible. Then assign A, B, C, and D to the four parts of the operon. Explain your rationale. (AE = active enzyme; IE = inactive enzyme; NE = no enzyme)
Genotype | tm Present | tm Absent |
A+B+C+D+ | AE | NE |
A–B+C+D+ | AE | AE |
A+B–C+D+ | NE | NE |
A+B+C–D+ | IE | NE |
A+B+C+D– | AE | AE |
A–B+C+D+/F′A+B+C+D+ | AE | AE |
A+B–C+D+/F′A+B+C+D+ | AE | NE |
A+B+C–D+/F′A+B+C+D+ | AE + IE | NE |
A+B+C+D–/F′A+B+C+D+ | AE | NE |
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