Upon hydrolysis of ATP is produces ADP and energy released due to breaking of one phosphide linkage.
we know the equilibrium constant and free energy are related with a formula, and also more the equilibrium constant more negative the free energy and more spontaneous the reaction will be.
but equilibrium constant is inversely proportional to [ATP] concentration.
hence for High ATP concentration , free energy will increases from more negative to less negative value.
5 Cellular ATP concentrations are maintained well above equilibrium concentrations in cells. Explain how high cellular...
er at initial change (AG The standard free energy change (AG) for ATP hydrolysis is -30.5 kJ/ mol ATP, ADP, and I are mixed together at initial concentrations of 1 M each then left alone until the reaction below has come to equilibrium. For each species (ie. ATP. ADP and P.) indicate whether the concentration will be equal to 1 M, less than 1 M, or greater than 1 M after the reaction had reached equilibrium. Explain why. ATP +...
We have seen all term that cells use the hydrolysis of high energy phosphate from ATP to make metabolic reactions thermodynamically favorable. Whereas most enzymes that utilize ATP hydrolyze between the b and g phosphates (yielding ADP + Pi), some enzymes hydrolyze ATP between the a and b phosphates (yielding AMP and PPi). ∆G°’ of phosphate hydrolysis is -31 kJ/mol for ATP + H2O --> ADP + Pi, and ∆G°’ of phosphate hydrolysis is -46.5 kJ/mol for ATP + H2O...
CHEM 351 Biochemistry I - Fall 2018 Study Problems for Metabolism and Glucose Catabolism For the reaction: aA + bB =cC + dD Gibbs free energy: AG = AG" + RT IN THE glucose + glucose 6-phosphate + H20 1. The equilibrium constant for phosphorylation of glucose is: Ke = 3.97 x 10- a. Calculate the standard Gibbs free energy for the uncatalyzed reaction. b. Use the physiological concentrations for glucose (2.0 mm) and inorganic phosphate (20 mM) to determine...
Can someone explain how cells use the hydrolysis of ATP to drive anabolic biological reactions. (in example, reactions where the free energy charge is positive)
I MIUI LIITUNU15YUUUUUUUUUUUUU. 1. What are the 3 (or 5) groups that make up the structure of ATP? 2. Why is the phosphoanhydride bond considered a high energy bond? 3. Is ATP hydrolysis a spontaneous or nonspontaneous reaction? Explain why. 4. What is being oxidized in ATP hydrolysis? What is being reduced? Explain why. 5. How do ATPases reduce the activation energy for ATP hydrolysis? 6. Why are energy carriers (also known as activated carriers) used in cellular respiration? Why...
1. Animal cells have a Na,K pump that couples the energy of ATP hydrolysis to transport 3 Na ions out of the cell and 2 K ions into the cell. Inside astrocytes, the concentration of Na is 20 mM and the concentration of K is 130 mM. The extracellular concentrations of Na and K are 145 mM and 5 mM, respectively. Calculate the energy required for the transport of Na and K , with this stoichiometry; assume that the cell...
GAP is the only 3 atom unit useful to produce ATP. However, under cellular conditions, TPI favors DHAP formation over GAP formation. How can glycolysis work? A. Glycolysis reactions that occur in stage 3, lower the concentration of GAP and drive glycolysis B. Aldolase reaction favors GAP formation C. ATP hydrolysis in stage 1 are irreversible and favor the formation of GAP D. TPI changes the equilibrium to favor GAP formation E. All of the above
and Q. Many metabolites are maintained at steady-state concentrations that are far from equilibrium. A comparison of K the mass-action ratio, can determine whether a metabolic reaction is far from equilibrium. The equation for this equilibrium is, fructose 6-phosphate + ATP fructose 1,6-bisphosphate + ADP Calculate for this reaction at T = 25.0°C. AG = -14.2 kJ/mol K Calculate the mass-action ratio, Q. from the approximate physiological concentrations for rat heart tissue shown in the table. Q Metabolite fructose 6-phosphate...
13. Describe 2 mechanisms whereby ATP is generated during cellular respiration Mechanism 1: Mechanism 2: 14. Indicate the MAIN molecules that enter and exit each of these processes? Molecule(s) IN Process Molecule(s) OUT Glycolysis Pyruvate Oxidation Citric Acid/Krebs Cycle ETC Photophosphorylation Calvin Cycle 15. Isocitrate is a 6 carbon molecule that is oxidized to a-ketoglutarate (a 5 carbon molecule) by the enzyme isocitrate dehydrogenase. What happens to the extra carbon atom in this reaction and in which process (listed in...
Please help with this question about Gibb's free energy. The answer is: -47.6 kJ/mol. Please show steps on how to find this answer! 1) In a rat hepatocyte, the concentrations of ATP, ADP and Pi are 3.4 mM, 1.3 mM and 4.8 mM, respectively. ATP + H2O → ADP + Pi + H+ a) Calculate the actual Gibb's free energy change for hydrolysis of ATP in this cell. ([H2O) = 1M; [H+] = 1M; R = 8.315 JK-mol-1; T =...