The osteoclast proton pump acidifies the outside of the cell to pH3 from a pH value...
The osteoclast proton pump acidifies the outside of the cell to pH3 from a pH value inside the cell of 7. The potential across the osteoclast plasma membrane is 60mV (inside more negative). Given intracellular concentrations of ADP = 1mM and phosphate = 0.5 mM, what ATP concentration is necessary to drive the transport of two moles of protons outside the cell per mole of ATP hydrolyzed? The temperature is 37°C, and the standard free energy change for ATP hydrolysis is – 30.5 kJ/mole
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![free energy of ATP hydrolysis under physiological conditions ATP + H20 = ADP + P equilibrium concentrations, [] eq, define AG](http://img.homeworklib.com/questions/1322dad0-9e7b-11ea-9e8d-ff02aad89e6d.png?x-oss-process=image/resize,w_560)
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The osteoclast proton pump acidifies the outside of the cell to
pH3 from a pH value...
V-type proton ATPase (proton pump): a: What type of transport is a V-type proton ATPase (an...
V-type proton ATPase (proton pump): a: What type of transport is a V-type proton ATPase (an integral membrane protein) uses ATP directly to transport protons across the membrane ? (PRIMARY OR SECONDARY) b: With the understanding of sodium-potassium pump, describe how a proton pump would use ATP to move protons against their concentration gradient (out of the cell) ? please do not say energy.
In considering active transport by Na+-K+-ATPase, 3 Na+ are pumped out of the cell and 2...
In considering active transport by Na+-K+-ATPase, 3 Na+ are pumped out of the cell and 2 K+ are pumped in for each ATP that is hydrolyzed to ADP + Pi. Given a ΔG for ATP hydrolysis of -10 kcal/mol, and that V is -60 mV (more electronegative inside), and that the pump typically maintains the internal Na+ at 10mM, external Na+ at 145 mM, internal K+ at 140 mM and external K+ at 5mM, what is the efficiency of the...
(a) For the following conditions, calculate the change in the Gibbs energy associated with transporting 1...
(a) For the following conditions, calculate the change in the Gibbs energy associated with transporting 1 mole of sodium ions from inside to outside the cell. Is work required or produced? Outside: [Na+] = 130 mM [K+] 5 mM Electrical potential = 0 mV [Na+]= [K 110 mM Electrical potential =-70 mV Temperature 25 °C Inside: 10 mM (b) For the same conditions, calculate the change in the Gibbs energy associated with transporting 1 mole of potassium ions from outside...
The transport of Na+ ions across a membrane, from a region where the concentration is 1 μM to a region where it is 100 μM, is coupled to the hydrolysis of ATP. Transport is opposed by a membrane poten...
The transport of Na+ ions across a membrane, from a region where the concentration is 1 μM to a region where it is 100 μM, is coupled to the hydrolysis of ATP. Transport is opposed by a membrane potential of 70 mV. Assuming energy coupling is 100% efficient, the hydrolysis of 1 mole of ATP can drive the transport of how many moles of Na+ at 37˚C if the ΔG for ATP hydrolysis is -53.4 kJ/mol under intracellular conditions?
The Na+/K+ pump transports 2 K+ into the cell and 3 Nat out of the cell...
The Na+/K+ pump transports 2 K+ into the cell and 3 Nat out of the cell under the use of ATP. Under normal circumstances, the concentration of K+ inside the cell is 140 mm, while the [K] outside of the cell is 6 mM. The concentration of Nat inside the cell is 16 mM, while the [Na] outside the cell is 145 mm. The membranpotential is -0.07 V The temperature is 37°C/310,15K c) Calculate how much energy (kJ/mol it takes...
1. Animal cells have a Na,K pump that couples the energy of ATP hydrolysis to transport 3 Na ions out of the cell and 2 K ions into the cell. Inside astrocytes, the concentration of Na is 20 mM and th...
1. Animal cells have a Na,K pump that couples the energy of ATP hydrolysis to transport 3 Na ions out of the cell and 2 K ions into the cell. Inside astrocytes, the concentration of Na is 20 mM and the concentration of K is 130 mM. The extracellular concentrations of Na and K are 145 mM and 5 mM, respectively. Calculate the energy required for the transport of Na and K , with this stoichiometry; assume that the cell...
1) According to the chemiosmotic theory, the synthesis of 1 mole of ATP is coupled to...
1) According to the chemiosmotic theory, the synthesis of 1 mole of ATP is coupled to the movement of 4 moles of H ions across the inner mitochondrial membrane (from outside to inside). Both the pH and the electrostatic potential (φ) can be different on different sides of the cell membrane as maintained by metabolic processes. a) Derive an expression for AG for the movement of 4 moles of H from outside the membrane to inside the membrane. Your expression...
How can dissolved materials be moved from the outside to the inside of a cell when...
How can dissolved materials be moved from the outside to the inside of a cell when the inside concentration of the material is higher than the outside concentration? a. Molecules can be moved into a cell against their concentration gradient if that transport is coupled with osmotic transport of water into the cell. b. Substances can be moved against a concentration gradient by pumps that do work using the energy provided by ATP hydrolysis. c. Some channels are capable of...
Cellular respiration: The Electron Transport Chain The breakdown of glucose ends during the Krebs cydle; however,...
Cellular respiration: The Electron Transport Chain The breakdown of glucose ends during the Krebs cydle; however, it is important to note that the energy previously contained in glucose is mostly stored in NADH and FADHz. In the last step of celular respiration, the high-energy electrons within NADH and FADH2 are passed within a set of proteins found in the inner membrane of the mitochondrion, collectively known as the electron transport chain. The electrons provide the energy to create ATP, which...
NUMBER 10 PLEASE -Kor Cor The Henry's law constant of oxygen in water at 25 °C...
NUMBER 10 PLEASE
-Kor Cor The Henry's law constant of oxygen in water at 25 °C is 773 atm mol'' kg of water. Calculate the molality of oxygen in water under a partial pressure of 0.20 atm. Assume that the solubility of oxygen in blood at 37 °C is roughly the same as that in water at 25 °C, comment on the prospect for our survival without hemoglobin molecules. The total volume of blood in the human body is about...
(a) For the following conditions, calculate the change in the Gibbs energy associated with transporting 1 mole of sodium ions from inside to outside the cell. Is work required or produced? Outside: [Na+] = 130 mM [K+] 5 mM Electrical potential = 0 mV [Na+]= [K 110 mM Electrical potential =-70 mV Temperature 25 °C Inside: 10 mM (b) For the same conditions, calculate the change in the Gibbs energy associated with transporting 1 mole of potassium ions from outside...
The Na+/K+ pump transports 2 K+ into the cell and 3 Nat out of the cell under the use of ATP. Under normal circumstances, the concentration of K+ inside the cell is 140 mm, while the [K] outside of the cell is 6 mM. The concentration of Nat inside the cell is 16 mM, while the [Na] outside the cell is 145 mm. The membranpotential is -0.07 V The temperature is 37°C/310,15K c) Calculate how much energy (kJ/mol it takes...
1) According to the chemiosmotic theory, the synthesis of 1 mole of ATP is coupled to the movement of 4 moles of H ions across the inner mitochondrial membrane (from outside to inside). Both the pH and the electrostatic potential (φ) can be different on different sides of the cell membrane as maintained by metabolic processes. a) Derive an expression for AG for the movement of 4 moles of H from outside the membrane to inside the membrane. Your expression...
Cellular respiration: The Electron Transport Chain The breakdown of glucose ends during the Krebs cydle; however, it is important to note that the energy previously contained in glucose is mostly stored in NADH and FADHz. In the last step of celular respiration, the high-energy electrons within NADH and FADH2 are passed within a set of proteins found in the inner membrane of the mitochondrion, collectively known as the electron transport chain. The electrons provide the energy to create ATP, which...
NUMBER 10 PLEASE
-Kor Cor The Henry's law constant of oxygen in water at 25 °C is 773 atm mol'' kg of water. Calculate the molality of oxygen in water under a partial pressure of 0.20 atm. Assume that the solubility of oxygen in blood at 37 °C is roughly the same as that in water at 25 °C, comment on the prospect for our survival without hemoglobin molecules. The total volume of blood in the human body is about...
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