Question

What are the the advantages and limitations of MS imaging compared to other imaging techniques?

Answer 1

Q.What are the the advantages and limitations of MS imaging compared to other imaging techniques?

Answer-:

Mass spectrometry imaging  is a technique used in mass spectrometry to visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses. After collecting a mass spectrum at one spot, the sample is moved to reach another region, and so on, until the entire sample is scanned.

Advantage-:

The main advantage of MSI for studying the molecules location and distribution within the tissue is that this analysis can provide either greater selectivity, more information or more accuracy than others. Moreover, this tool requires less investment of time and resources for similar results.

1.multiplex

2.label free imaging

3.good spatial resolution.

Disadvantage-:

1.semi quantitative

2.ion suppression effect

3.complex analysis.