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What happens if the wrong nucleotide is added during RNA transcription?

What happens if the wrong nucleotide is added during RNA transcription?

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If the wrong nucleotide is added during RNA transcription, spontaneous mutation will be produced as a result it is going to lead ending of the premature mRNA formation or during translation, a truncated nonfunctional protein may be produced in the phenotype. Thereby it is essential to perform proof reading of the transcript during transcription by RNA polymerase. Soem times, spliceosomes may remove this wrong nucleiotide by splicing when maturation of pre-mRNA to mRNA is going to be done after transcription.

Normally RNA polymerase will repair this error and will backtrack; if not it is going to produce premature stop codons during the transcription with high error rate. Thereby nonsense-mediated decay is essential.

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