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The pedigree below that shows a family in which an autosomal recessive disorder is present. Family...
The given image shows the pedigree of a family with an autosomal recessive disorder. Analyze the...
The given image shows the pedigree of a family with an autosomal
recessive disorder. Analyze the pedigree to determine the
probability of individual 12 being a carrier. Please write your
answer as a probability from 0 to 1. Probability:
The pedigree below illustrates a family that has an autosomal recessive disorder running through it. The...
The pedigree below illustrates a family that has an autosomal recessive disorder running through it. The pedigree does not show you who the unaffected carriers are, however-all the unaffected carriers have been drawn as unaffected, without the dots that should be in their symbols. Please tell me everyone who must be a carrier-don't tell me who could be a carrier-tell me who MUST be a carrier.
The pedigree below shows the inheritance pattern of a sex-linked allele for one family. What is...
The pedigree below shows the inheritance pattern of a sex-linked allele for one family. What is true about the genotype of individuall-2? 1-1 1-2 II-1 II-2 II-3 II-4 III-1 III-2 The disease is caused by a dominant allele (D) and his genotype is dd He must have the genotype X'Y The disease is caused by having two recessive alleles (dd) and his genotype is He has the recessive disease allele on his X chromosome XY He has the dominant disease...
You are mapping a rare autosomal recessive disorder and linkage points towards a location on chromosome...
You are mapping a rare autosomal recessive disorder and linkage points towards a location on chromosome 7. To refine the location of the disease gene, you determine the genotype for 11 additional markers that map to an approximately 65 Mb region on the long arm of chromosome 7. Alleles for each of these markers are shown for one family. What type of markers are most likely shown? Why do you know this?
The pedigree shows the occurrence of a X linked recessive mendelian disease in a human family....
The pedigree shows the occurrence of a X linked recessive mendelian disease in a human family. Two unaffected family members were genotyped at a microsatellite locus and two different microsatellite alleles were observed (M1 and M2) I M1/M1 II 1 M1 M2 III 3 IV 3 5 a) Assume the disease and the microsatellite locus are completely linked. What is the genotype of individual IV-4 (give both disease and micrsatellite alleles in the genotype)? b) Assume that the disease locus...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
11. (8 m) Refer to the following pedigree, which traces the inheritance of a biochemical disorder....
11. (8 m) Refer to the following pedigree, which traces the inheritance of a biochemical disorder. female not affected female affected 0 male not affected male affected a. (2 m) Does this disorder appear to be caused by an autosomal or sex-linked gene? Does this disorder appear to be caused by a dominant allele or by a recessive allele? Explain how you know this. b. (2 m) Fill in the genotypes of all affected individuals. Use A and a to...
Betsy has an autosomal recessive disorder. Kevin is a carrier. They have one boy (II-3) who...
Betsy has an autosomal recessive disorder. Kevin is a carrier.
They have one boy (II-3) who has the same autosomal recessive
disorder as his mom.
On the gel, thick bands represent twice as much DNA as thin
bands (kb = kilobases = length). Betsy is homozygous for the 4-kb
mutant allele. Kevin is heterozygous for the 4-kb mutant allele and
the 15-kb normal allele.
Which of the following situations could explain the genotype of
their first son (II-2)?
A. Normal...
22. In the pedigree shown below it has been found that the disease (indicated by the...
22. In the pedigree shown below it has been found that the disease (indicated by the filled circles) is caused by a RARE autosomal recessive mutation in a gene that is paternally imprinted. What are the genotype(s) for individuals 1-2 and II-4, respectively? Imprinted alleles are identified with an asterisk. 1 II 6 성 모 . III 5 A) aa* and AA* B) aA* and Aa* C) aa* and Aa* D) Aa* and AA* E) aA* and AA*
14. Huntington's Disease, an autosomal dominant disorder, was linked to a Hindill digestion site using a...
14. Huntington's Disease, an autosomal dominant disorder, was linked to a Hindill digestion site using a Southern Blot and a specific probe. Researchers detected four different digestion patterns, three of which are below (called haplotypes A, B, and C). Haplotype A is linked to the defective huntingtingene, which causes neurodegeneration. a. Which individuals (#1-7) have Huntington's Disease? b. Which band size on the gel represents haplotype B? C. A person has bands only at 3.7/1.2 kb (not 4.9 kb) but...
The given image shows the pedigree of a family with an autosomal
recessive disorder. Analyze the pedigree to determine the
probability of individual 12 being a carrier. Please write your
answer as a probability from 0 to 1. Probability:
The pedigree below illustrates a family that has an autosomal recessive disorder running through it. The pedigree does not show you who the unaffected carriers are, however-all the unaffected carriers have been drawn as unaffected, without the dots that should be in their symbols. Please tell me everyone who must be a carrier-don't tell me who could be a carrier-tell me who MUST be a carrier.
The pedigree below shows the inheritance pattern of a sex-linked allele for one family. What is true about the genotype of individuall-2? 1-1 1-2 II-1 II-2 II-3 II-4 III-1 III-2 The disease is caused by a dominant allele (D) and his genotype is dd He must have the genotype X'Y The disease is caused by having two recessive alleles (dd) and his genotype is He has the recessive disease allele on his X chromosome XY He has the dominant disease...
You are mapping a rare autosomal recessive disorder and linkage points towards a location on chromosome 7. To refine the location of the disease gene, you determine the genotype for 11 additional markers that map to an approximately 65 Mb region on the long arm of chromosome 7. Alleles for each of these markers are shown for one family. What type of markers are most likely shown? Why do you know this?
The pedigree shows the occurrence of a X linked recessive mendelian disease in a human family. Two unaffected family members were genotyped at a microsatellite locus and two different microsatellite alleles were observed (M1 and M2) I M1/M1 II 1 M1 M2 III 3 IV 3 5 a) Assume the disease and the microsatellite locus are completely linked. What is the genotype of individual IV-4 (give both disease and micrsatellite alleles in the genotype)? b) Assume that the disease locus...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
11. (8 m) Refer to the following pedigree, which traces the inheritance of a biochemical disorder. female not affected female affected 0 male not affected male affected a. (2 m) Does this disorder appear to be caused by an autosomal or sex-linked gene? Does this disorder appear to be caused by a dominant allele or by a recessive allele? Explain how you know this. b. (2 m) Fill in the genotypes of all affected individuals. Use A and a to...
Betsy has an autosomal recessive disorder. Kevin is a carrier.
They have one boy (II-3) who has the same autosomal recessive
disorder as his mom.
On the gel, thick bands represent twice as much DNA as thin
bands (kb = kilobases = length). Betsy is homozygous for the 4-kb
mutant allele. Kevin is heterozygous for the 4-kb mutant allele and
the 15-kb normal allele.
Which of the following situations could explain the genotype of
their first son (II-2)?
A. Normal...
22. In the pedigree shown below it has been found that the disease (indicated by the filled circles) is caused by a RARE autosomal recessive mutation in a gene that is paternally imprinted. What are the genotype(s) for individuals 1-2 and II-4, respectively? Imprinted alleles are identified with an asterisk. 1 II 6 성 모 . III 5 A) aa* and AA* B) aA* and Aa* C) aa* and Aa* D) Aa* and AA* E) aA* and AA*
14. Huntington's Disease, an autosomal dominant disorder, was linked to a Hindill digestion site using a Southern Blot and a specific probe. Researchers detected four different digestion patterns, three of which are below (called haplotypes A, B, and C). Haplotype A is linked to the defective huntingtingene, which causes neurodegeneration. a. Which individuals (#1-7) have Huntington's Disease? b. Which band size on the gel represents haplotype B? C. A person has bands only at 3.7/1.2 kb (not 4.9 kb) but...
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