In the absence of infection ____________________ (Select all that apply).
1. MHC class I and class II molecules bind to and transport self peptides to the cell surface
2. MHC class I and class II molecules are unable to progress through the vesicular system
3. MHC class II molecules bind to self peptides prematurely in the lumen of the endoplasmic reticulum
4. non-self peptides do not bind to MHC molecules
1.MHC class I and class II molecules bind to and transport self peptides to the cell surface.
3. MHCclass II molecules bind to self peptides prematurely in the lumen of the endoplasmic reticulum
In the absence of infection ____________________ (Select all that apply). 1. MHC class I and class...
In the absence of infection ____________________ (Select all that apply). 1. MHC class I and class II molecules bind to and transport self peptides to the cell surface 2. MHC class I and class II molecules are unable to progress through the vesicular system 3. MHC class II molecules bind to self peptides prematurely in the lumen of the endoplasmic reticulum 4. non-self peptides do not bind to MHC molecules Please select all correct answers. Thank you.
In the absence of infection ____________________ (Select all that apply). Group of answer choices A. MHC class II molecules bind to self peptides prematurely in the lumen of the endoplasmic reticulum B. non-self peptides do not bind to MHC molecules C. MHC class I and class II molecules bind to and transport self peptides to the cell surface D. MHC class I and class II molecules are unable to progress through the vesicular system
1. Autoimmunity is most likely to occur when A. An antigen impinges upon the immune system that crossreacts with a peripheral self-antigen. b. complement is activated c. toxins are produced by bacteria, causing tissue damage. d. an infection occurs that is prolonged. 2. What is (are) common to both MHC class 1 molecules and MHC class 2 molecules? choose the most correct answer a. both show limited variability from one individual to another. b. both bind peptides generated within the...
Handout IG2-2 Class I MHC-Peptide Interactions Place the steps of the antigen-processing pathway for endogenous antigen in the correct order Alpha chain of class I MHC binds peptide. Endogenous antigen within cytosol is degraded by proteasome. Peptides are transported into endoplasmic reticulum by TAP Alpha chain of class I MHC binds β2-microglobulin. Peptide-class I MHC is transported to Golgj complex and then to cell surface. Class I MHC peptide binds to CD8+T cell.
Question 13 3 pt: MHC I and MHC Il differ from each other in that: MHC I, but not MHC II, is necessary for T cells to kill cells presenting endogenous antigen MHC I, but not MHC II, primarily present exogenous antigens to CD8+ T cells MHC I, but not MHC II, is necessary for T cells to activate B cells MHC II, but not MHC I, primarily present endogenous antigens to CD4+ T cells Question 14 3 pts In...
During negative selection MHC class I and Il molecules on the surface of thymic epithelial cells Select one: Present peptides derived from self proteins present in the thymus b. Do not have any peptides bound to them c. Present only peptides derive from self proteins transported to the thymus from the periphery d. Present only peptides derived from self MHC molecules
The immune system is self-restricted and the self-restriction is
seen with immunological responses that involve both the MHC class I
and the MHC class II molecules. Define MHC class I and class II
restriction, which molecules and cells are involved and which stage
of the immune response (stages 1 – 8 in figure 1-7) the class I and
class II restriction occurs (pick a stage from figure 1-7, state
that stage, and describe the MHC restriction taking place (class I...
Immunology
The immune system is self-restricted and the self-restriction is
seen with immunological responses that involve both the MHC class I
and the MHC class II molecules. Define MHC class I and class II
restriction, which molecules and cells are involved and which stage
of the immune response (stages 1 – 8 in figure 1-7 on page 20) the
class I and class II restriction occurs (pick a stage from figure
1-7, state that stage, and describe the MHC restriction...
answer all the questions answering one question is not helpful 1. A helper T cell is capable of helping another cell because it expresses a protein on its surface that binds to a different protein on the surface of the cell being helped. What are these proteins (on the T cell, and on the cell being helped)? CD28, and B7 TNF, and TNFR Class I MHC, and TCR CD40L, and CD40 CTLA-4, and B7 2. Helper T cells are restricted...
The transporter in antigen processing genes encode subunits of a heterodimer pump that transports peptides from the cytosol into the endoplasmic reticulum, where they can associate with newly translated Class la chains O B-2 microglobulin. Proteosomes. Immunoglobulin molecules. Class Il a and B chains. Question 20 5 pts Soluble proteins are examples of: Bone marrow dependent antigens. Bone marrow independent antigens., Thymus dependent antigens. Thymus independent antigens. Good food. The features of bound peptide fragments isolated from different class molecules...