A. what does chloroquine do to double-stranded DNA:
B: Based on this, what might its effect be on the Corona virus ?
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A. what does chloroquine do to double-stranded DNA: B: Based on this, what might its effect...
27. What is the tm for a double-stranded DNA? How does it qualitatively depend in its nucleotide composition?
3) DNA polymerases that have an editing function bind to and encircle double-stranded DNA in their "palm" domain, and grip the double-stranded DNA tightly between their "thumb" and "fingers" domains. Since they can bind to any DNA double helix regardless of its sequence, which groove in DNA do you think they sample ("feel") for correct helix geometry? a) The minor groove b) The major groove c) Either of the above is equally probable
Which of the following shows a double-stranded segment of DNA that might be cut by a restriction enzyme? 5’ GACTGACT 3’ 3’ CTGACTGA 5’ 5’ GAGGAG 3’ 3’ CTCCTC 5’ 5’ GAATTC 3’ 3’ CTTAAG 5’
Two complementary strands of DNA can exist in solution in the form of a duplex (double-stranded form) or can exist as separate strands ("random coils"), depending on the position of the equilibrium shown below. Double-stranded form < = = > single strands ("random coil") With regard to Enthalpy and Entropy, match the interactions that favor the form of DNA listed. What is the enthalpic term favoring single stranded DNA? A. Hydrogen Bonding B. Conformational C. Base Stacking D. van der...
Single stranded DNA (ssDNA) is a product of DNA denaturation. When compared to double stranded DNA (dsDNA) it is much more flexible with its persistence length (lp) estimated to be an order of magnitude lower than that for dsDNA. If a particular dsDNA sequence has a (4-63 nm): a) Estimate at what concentration of NaCl dsDNA flexibility is comparable to that of ssDNA [NaCl]- a) Estimate at what concentration of MgCl2 dsDNA flexibility is comparable to that of SSDNA [MgCl2]-
What is the average radius of a piece of double-stranded DNA in water that has a link length of 5.9 nm and and is 3019228 links long If the two strands of the double-stranded DNA are separated, each chain now has a radius of 530 nm. What is the link length for single-stranded DNA?
QUESTION 9 Strand invasion requires a__, O A. 5', single-stranded B. 5', double-stranded ° C. 3, single-stranded O D.3', double-stranded DNA molecule. QUESTION 10 The form of genetic recombination that allows movement of genetic elements from one DNA site to another is termed: O A site-specific recombination O B. homologous recombination ° C. branch migration D.transposition QUESTION 9 Strand invasion requires a__, O A. 5', single-stranded B. 5', double-stranded ° C. 3, single-stranded O D.3', double-stranded DNA molecule. QUESTION 10...
What part(s) of a nucleotide will occupy the major & minor groove of a double-stranded DNA molecule? WHY? What parts are found in the DNA backbone? WHY? Where would a Restriction Endonuclease associate with DNA? How long is a double-stranded DNA molecule that is 2 x 105 bp? How many nucleosomes would be required to package this DNA if it were in a Eukaryote? When chromatin from any eukaryote is digested briefly with micrococcal nuclease (an endonuclease) and fractionated using...
What is the consequence of a transition mutation in double-stranded DNA? A purine is replaced by another purine, or a pyrimidine is replaced by another pyrimidine. A base pair is lost within the DNA of a gene, which causes a reading frameshift. The parent, but not its offspring, will be affected by the mutation. A base pair is added to the DNA within a gene, which causes a reading frameshift. A purine is replaced by a pyrimidine, or a pyrimidine...
What one of the followings will finish DNA synthesis to make complete double stranded DNA if there is only DNA polymerase III? (provide reasons for why all of them cannot do DNA replication in this situation) 5'-GGGGTTGGGGATTT-3' 3'-CCCCAACCCCTAAA-5' 5'-GGGGATTT-3' D) 3'-CCCCAACCCCTAAA-5' c) 5'-GGGGTTGGGGATTT-3' 3'-CCCCUAAA-5' d) 5'-GGGGTTGGGGATTT-3' 3'-CCCCTAAA-5' e) 5' -GGGGTTGGGG-3' 3'-CCCCTAAA-5°