Does arginine play a role in acid/base catalysis, covalent catalysis or both? Explain your answer?
Does arginine play a role in acid/base catalysis, covalent catalysis or both? Explain your answer?
Homework Answers
Arginine is a basic amino acid. It has a high pka value. But it can be used for catalysis of certain oxidation in the form of cleavage reaction.
It does not act strongly as covalent catalyst because of its high pka value.
Add Answer to:
Does arginine play a role in acid/base catalysis,
covalent catalysis or both? Explain your answer?
Enzymes use several types of catalytic mechanisms. Differentiate between acid-base catalysis, covalent catalysis, and metal ion...
Enzymes use several types of catalytic mechanisms. Differentiate
between acid-base catalysis, covalent catalysis, and metal ion
catalysis.
Categorize these correctly
Enzymes use several types of catalytic mechanisms. Differentiate between acid-base catalysis, covalent catalysis, and metal ion catalysis.
Are the following examples of general acid/base catalysis, covalent catalysis, catalysis by approximation (proximity effect), or...
Are the following examples of general acid/base catalysis, covalent
catalysis, catalysis by approximation (proximity effect), or
metal-ion catalysis? Complete parts a, b, c, and d.
(b) NMP kinases bring two nucleotides, for example AMP and ATP,
together to facilitate the transfer of a phosphoryl group from one
nucleotide to the other (creating two ADP). The enzyme positions
the adenosine triphosphate (ATP) such that the gamma phosphate
group is placed adjacently to the phosphate group of the NMP
kinase. This facilitates...
The HIV protease enzyme uses a general acid-base catalysis mechanism to cleave viral polypeptides but does...
The HIV protease enzyme uses a general acid-base catalysis mechanism to cleave viral polypeptides but does not use a covalent catalysis. This enzyme functions optimally in the pH range of 4-6. Due to the specific amino acids involved in this catalysis, HIV protease is a member of which subclass of proteases? Select one: A. metalloproteases B. aspartyl proteases C. serine proteases D. lysine proteases E. cysteine proteases
Chymotrypsin What evidence in chymotrypsin mechanism supports the claim that chymotrypsin catalysis involves general acid-base catalysis...
Chymotrypsin What evidence in chymotrypsin mechanism supports the claim that chymotrypsin catalysis involves general acid-base catalysis and covalent catalysis? Draw the chemical structure of the transition state (resembles the intermediate structure) in the step that forms the enzyme-product covalent adduct. In comparison to the substrate, how is the tetrahedral transition state preferentially stabilized by enzyme? Chymotrypsin mechanism: Write all the steps in the mechanism and understand what each step accomplishes.
2) A) Amino acids such as Phe and Val are not known to participate directly in acid-base or coval...
2) A) Amino acids such as Phe and Val are not known to participate directly in acid-base or covalent catalysis. Explain why B) Mutating a Phe and Val can still have dramatic effects on enzyme activity. Why?
2) A) Amino acids such as Phe and Val are not known to participate directly in acid-base or covalent catalysis. Explain why B) Mutating a Phe and Val can still have dramatic effects on enzyme activity. Why?
What role does glutamine play in amino acid metabolism of plants and how is it affected...
What role does glutamine play in amino acid metabolism of plants and how is it affected by light?
1) What role does the active site lysine play in the mechanism of CO2 fixation in Rubisco? Hypoth...
1) What role does the active site lysine play in the mechanism of CO2 fixation in Rubisco? Hypothesize what effect the mutation of this lysine to arginine would have on the protein.
Is ncRNA linked to mRNA by covalent bonds, base complementary or both? What effect does this...
Is ncRNA linked to mRNA by covalent bonds, base complementary or both? What effect does this have on the transcript?
What role does personal ethics play in a decision-making process? explain
What role does personal ethics play in a decision-making process? explain
What role (if any) does temperature play in the Nernst equation? Explain how this relates to...
What role (if any) does temperature play in the Nernst equation? Explain how this relates to your findings. What properties of the ion channels may change with temperature?
Enzymes use several types of catalytic mechanisms. Differentiate
between acid-base catalysis, covalent catalysis, and metal ion
catalysis.
Categorize these correctly
Enzymes use several types of catalytic mechanisms. Differentiate between acid-base catalysis, covalent catalysis, and metal ion catalysis.
Are the following examples of general acid/base catalysis, covalent
catalysis, catalysis by approximation (proximity effect), or
metal-ion catalysis? Complete parts a, b, c, and d.
(b) NMP kinases bring two nucleotides, for example AMP and ATP,
together to facilitate the transfer of a phosphoryl group from one
nucleotide to the other (creating two ADP). The enzyme positions
the adenosine triphosphate (ATP) such that the gamma phosphate
group is placed adjacently to the phosphate group of the NMP
kinase. This facilitates...
The HIV protease enzyme uses a general acid-base catalysis mechanism to cleave viral polypeptides but does not use a covalent catalysis. This enzyme functions optimally in the pH range of 4-6. Due to the specific amino acids involved in this catalysis, HIV protease is a member of which subclass of proteases? Select one: A. metalloproteases B. aspartyl proteases C. serine proteases D. lysine proteases E. cysteine proteases
2) A) Amino acids such as Phe and Val are not known to participate directly in acid-base or covalent catalysis. Explain why B) Mutating a Phe and Val can still have dramatic effects on enzyme activity. Why?
2) A) Amino acids such as Phe and Val are not known to participate directly in acid-base or covalent catalysis. Explain why B) Mutating a Phe and Val can still have dramatic effects on enzyme activity. Why?
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