A ____________ converts a wildtype allele into a mutant allele, while ______________ convert a mutant allele...
A ____________ converts a wildtype allele into a mutant allele, while ______________ convert a mutant allele into a wildtype allele or wildtype state.
Homework Answers
A forword mutation converts a wildtype allele into a mutant allele, while reversion mutation convert a mutant allele into a wildtype allele or wildtype state.
A forward mutation changes a functional or wild type allele to a nonfunctional or mutant allele while a back mutation or reversion is a point mutation that restores the original sequence( i. e. wild type).
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A ____________ converts a wildtype allele into a mutant allele,
while ______________ convert a mutant allele...
You are studying two different forms of an enzyme. One form is from the wildtype allele....
You are studying two different forms of an enzyme. One form is
from the wildtype allele. The other is a mutant version. A partial
sequence of the wildtype allele is shown here. The underlined area
is of particular interest to you, since it includes where the
mutation may occur. Design a set of 9nt primers that will
successfully amplify this region. Be sure to write the primers in
the correct orientation, as is typical for molecular
biologists.
forward primer sequence:...
Given an individual who is heterozygous for a recessive disease (i.e., the wildtype allele is dominant),...
Given an individual who is heterozygous for a recessive disease (i.e., the wildtype allele is dominant), explain how a deletion could result in the expression of the recessive phenotype. Be sure to use the formal vocabulary for full points.
Heterozygotes for a loss of expression allele of the methyl CpG binding protein 2 (MECP2) gene...
Heterozygotes for a loss of expression allele of the methyl CpG binding protein 2 (MECP2) gene can develop Rett syndrome, which affects about one in ten thousand people. Select all of the following that accurately describe the Rett associated allele of MECP2. Group of answer choices dominant negative wildtype at organismal level dominant gain-of-function mutant at molecular level not wildtype at organismal level dominant loss-of-function wildtype at molecular level dominant haploinsufficiency recessive loss of function
3A) If both parents are heterozygous carriers of a mutant allele, what is the chance that...
3A) If both parents are heterozygous carriers of a mutant allele, what is the chance that their first child will be homozygous recessive for the mutation? 3B) Parents who are each heterozygous carriers for a recessive mutant allele have a child who does not have the condition. What is the chance this child is a heterozygous carrier of the condition? 3C) If the first child of parents who are both heterozygous carriers of a recessive mutant allele is homozygous recessive,...
A certain disease is caused by a recessive mutant allele. (The wild-type allele is dominant.) However,...
A certain disease is caused by a recessive mutant allele. (The wild-type allele is dominant.) However, the penetrance of the disease is 75%. Two individuals known to be heterozygotes have a child. What is the probability that the child exhibits the disease?
6 A human trait that is caused by an autosomal dominant mutant allele has a penetrance...
6
A human trait that is caused by an autosomal dominant mutant allele has a penetrance of 50%. A man who is heterozygous for this mutant allele marries a woman who is homozygous recessive for the normal allele. If they have two children then what is the probability that both children will show the normal phenotype? O 1/4 o 1/2 03/16 0 7/8 09/16
t cells that are wildtype for the genes in the adenine pathway are of growing on...
t cells that are wildtype for the genes in the adenine pathway are of growing on minimal media lacking adenine. In parallel experiments, we O treat a wildtype culture of yeast cells with one of three mutagens: nitrous acid (a deaminating agent), UV light, and the intercalating agent, acridine orange. We obtain several adenine deficient colonies [ade- with each of the treatments and one mutant from each treatment condition is chosen for further analysis. DNA sequence analysis reveals that each...
You cross a Drosophila female with kidney-shaped and brown eyes with a male that has wildtype...
You cross a Drosophila female with kidney-shaped and brown eyes with a male that has wildtype eye shape and color. Kidney-shaped eyes are found in females that are heterozygous for the bar eyed mutation. Bar eyed females are homozygous for the bar eyed mutant allele, whereas bar eyed males are hemizygous for the mutation. Brown eyes are an autosomal recessive mutation. Attention: Half of the resulting F1 has brown eyes! [...
4. In Drosophila melanogaster, the phenotype curly wings is due to a mutant allele Cy that...
4. In Drosophila melanogaster, the phenotype curly wings is due to a mutant allele Cy that is lethal when homozygous. A population is established with an initial frequency of Cy equal to 0.168. Denoting + as the wild- type (i.e. non-mutant) allele at this locus, calculate the expected frequency of Cy in the next generation if the relative fitness of the ++ homozygote to the Cy/+ heterozygote is: a) 1 : 1 b) 1 : 0.5 c) Briefly explain why...
Albinism is a genetic disorder caused by an autosomal recessive allele. The dominant allele results in...
Albinism is a genetic disorder caused by an autosomal recessive allele. The dominant allele results in the wildtype pigmentation. a) If an albino marries a homozygous person for the wildtype pigmentation allele, what would be the expected phenotype and genotype of their children? b) If an albino marries a person with wildtype pigmentation but that carries the albino allele, what would be the expected phenotypes and genotypes of their children? c) Two parents of wildtype pigmentation had an albino child....
You are studying two different forms of an enzyme. One form is
from the wildtype allele. The other is a mutant version. A partial
sequence of the wildtype allele is shown here. The underlined area
is of particular interest to you, since it includes where the
mutation may occur. Design a set of 9nt primers that will
successfully amplify this region. Be sure to write the primers in
the correct orientation, as is typical for molecular
biologists.
forward primer sequence:...
6
A human trait that is caused by an autosomal dominant mutant allele has a penetrance of 50%. A man who is heterozygous for this mutant allele marries a woman who is homozygous recessive for the normal allele. If they have two children then what is the probability that both children will show the normal phenotype? O 1/4 o 1/2 03/16 0 7/8 09/16
t cells that are wildtype for the genes in the adenine pathway are of growing on minimal media lacking adenine. In parallel experiments, we O treat a wildtype culture of yeast cells with one of three mutagens: nitrous acid (a deaminating agent), UV light, and the intercalating agent, acridine orange. We obtain several adenine deficient colonies [ade- with each of the treatments and one mutant from each treatment condition is chosen for further analysis. DNA sequence analysis reveals that each...
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