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A rare human disease is found in a family as shown in the accompanying pedigree. a)...
The following pedigree represents the inheritance of a rare disorder in a large family What is...
The following pedigree represents the inheritance of a rare
disorder in a large
family What is the most likely mode of inheritance? Why?
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Question 3 The following human pedigree shows a family affected by a specific disease. Assume that...
Question 3 The following human pedigree shows a family affected by a specific disease. Assume that the individuals marked with an asterisk () do not carry any allele associated with the affected phenotype and that no other mutation spontaneously occurs. Also assume complete penetrance a) State the most likely mode of inheritance for this disease. Choose from: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive b) Write all possible genotypes of the following individuals in the pedigree. Use the uppercase...
Please provide a detailed explanation. 63. The accompanying pedigree concerns a rare inherited dental abnormality, amelogenesis...
Please provide a detailed explanation.
63. The accompanying pedigree concerns a rare inherited dental abnormality, amelogenesis imperfecta. S SIS a. What mode of inheritance best accounts for the transmission of this trait? b. Write the genotypes of all family members according to your hypothesis.
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
1. Human inheritance patterns (5 pts). All of the following questions refer to the following pedigree,...
1. Human inheritance patterns (5 pts). All of the following questions refer to the following pedigree, tracing a rare trait (#1) and a common trait (#2) through the same family. (We are combining two different charts into one chart with this method. It may help you to redraw two separate charts to make who is affected/unaffected by each trait more clear. The inheritance of trait 1 doesn't influence the inheritance of trait 2.) 1 - Affected Trait 1 - Affected...
Tay-Sachs disease (infantile amaurotic idiocy) is a rare human disease in which toxic substances ...
Tay-Sachs disease (infantile amaurotic idiocy) is a rare human disease in which toxic substances accumulate in nerve cells. The recessive allele responsible for the disease is inherited in a simple Mendelian manner. A woman is planning to marry her first cousin (their fathers are brothers), but the couple discovers that their shared grandfather's sister died in infancy of Tay-Sachs disease and their shared great grandparents didn't have this disease. What is the probability that the cousins' first child will have...
Styles 6. Insert a picture of your pedigree chart for this family with genotypes filled in...
Styles 6. Insert a picture of your pedigree chart for this family with genotypes filled in here. 7. Which pattern of inheritance do you think the disease shows? Explain your reasoning. 8. Patient 1 and Patient 2 in the pedigree chart would like to know what the chances are that they will have a child with the disease. What do you tell them? Use a Punnett Square to show your work. Using Punnett Squares for human conditions and diseases The...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
The pedigree below shows a family with a rare late-onset X-linked disease that is 8 m.u....
The pedigree below shows a family with a rare late-onset X-linked disease that is 8 m.u. from the STR locus R5T. The STR genotype is shown below each person. What is the probability II-1 will develop the disease later in life? 2,3 4 3 2,4 Select one: a. 8% b. 46% c. 92% d. O e. 4%
The pedigree shows the occurrence of a X linked recessive mendelian disease in a human family....
The pedigree shows the occurrence of a X linked recessive mendelian disease in a human family. Two unaffected family members were genotyped at a microsatellite locus and two different microsatellite alleles were observed (M1 and M2) I M1/M1 II 1 M1 M2 III 3 IV 3 5 a) Assume the disease and the microsatellite locus are completely linked. What is the genotype of individual IV-4 (give both disease and micrsatellite alleles in the genotype)? b) Assume that the disease locus...
The following pedigree represents the inheritance of a rare
disorder in a large
family What is the most likely mode of inheritance? Why?
" " ;; ਆਰ ;;
Question 3 The following human pedigree shows a family affected by a specific disease. Assume that the individuals marked with an asterisk () do not carry any allele associated with the affected phenotype and that no other mutation spontaneously occurs. Also assume complete penetrance a) State the most likely mode of inheritance for this disease. Choose from: autosomal dominant, autosomal recessive, X-linked dominant, X-linked recessive b) Write all possible genotypes of the following individuals in the pedigree. Use the uppercase...
Please provide a detailed explanation.
63. The accompanying pedigree concerns a rare inherited dental abnormality, amelogenesis imperfecta. S SIS a. What mode of inheritance best accounts for the transmission of this trait? b. Write the genotypes of all family members according to your hypothesis.
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
1. Human inheritance patterns (5 pts). All of the following questions refer to the following pedigree, tracing a rare trait (#1) and a common trait (#2) through the same family. (We are combining two different charts into one chart with this method. It may help you to redraw two separate charts to make who is affected/unaffected by each trait more clear. The inheritance of trait 1 doesn't influence the inheritance of trait 2.) 1 - Affected Trait 1 - Affected...
Tay-Sachs disease (infantile amaurotic idiocy) is a rare human disease in which toxic substances accumulate in nerve cells. The recessive allele responsible for the disease is inherited in a simple Mendelian manner. A woman is planning to marry her first cousin (their fathers are brothers), but the couple discovers that their shared grandfather's sister died in infancy of Tay-Sachs disease and their shared great grandparents didn't have this disease. What is the probability that the cousins' first child will have...
Styles 6. Insert a picture of your pedigree chart for this family with genotypes filled in here. 7. Which pattern of inheritance do you think the disease shows? Explain your reasoning. 8. Patient 1 and Patient 2 in the pedigree chart would like to know what the chances are that they will have a child with the disease. What do you tell them? Use a Punnett Square to show your work. Using Punnett Squares for human conditions and diseases The...
Creating a pedigree chart from a family history and hypothesizing pattern of inheritance A family with a new disease caused by a mutant gene has been found. The family history has been collected and recorded. You will now create a pedigree chart from their family history and use the pedigree to predict the pattern of inheritance the disease follows. • Read the following family history: Patient 1 and Patient 2 visited a genetics counselor and provided their family histories. As...
The pedigree below shows a family with a rare late-onset X-linked disease that is 8 m.u. from the STR locus R5T. The STR genotype is shown below each person. What is the probability II-1 will develop the disease later in life? 2,3 4 3 2,4 Select one: a. 8% b. 46% c. 92% d. O e. 4%
The pedigree shows the occurrence of a X linked recessive mendelian disease in a human family. Two unaffected family members were genotyped at a microsatellite locus and two different microsatellite alleles were observed (M1 and M2) I M1/M1 II 1 M1 M2 III 3 IV 3 5 a) Assume the disease and the microsatellite locus are completely linked. What is the genotype of individual IV-4 (give both disease and micrsatellite alleles in the genotype)? b) Assume that the disease locus...
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