Question

What type of physical mutations are most likely to cause a hypomorph? O A nonsense O B missense C frameshift o D silent O E polymorphism

Answer 1

Answer =

The type of physical mutations are most likely to cause a hypomorph are

A.Nonsense mutation-

Explanation - A hypomorphic mutation a mutation that causes a partial loss of gene function.hypomorph is a reduction in gene function through reduced protein or RNA expression or reduced functional performance, but not complete loss.

Nonsense mutation- Is a type of mutation that changes a codon in a gene to one of the three termination codons.this mutation results in a shortened protein because translation of the mRNA stops at this new termination codon.this mutation occurs a premature nonsense or stop codon is introduced in the DNA sequence.when this mutated sequence is translated into a protein, the resulting protein is incomplete and shorter than normal.

this mutation is results in shorter , unfinshed protein product.

INCORRECT OPTIONS ARE :

B.Missense mutation- The mutation that alters the codon so that it specifies a different amino acid .the result of this mutation is not shortens the protein length.

C.Frameshift mutation = is a type mutation in which small numbers of extra nucleotides being inserted or deleted from the polynucleotide being synthesized.

therefore this mutation result in the abnormal protein product with a n incorrect amino acid sequence that can be either longer or shorter than the normal protein.

D.Silent mutation - mutation without apparent effect called as silent mutation.

E.Polymorphism - is the presence of more than one allele at a particular locus in a particular population.