Question

1. Explain the difference between spontaneous and induced mutations. Give an example of how each might...

1. Explain the difference between spontaneous and induced mutations. Give an example of how each might be caused

2. For the double stranded DNA molecule shown below, the BOTTOM strand is the template for transcription. The START CODON is AUG and the STOP CODON IS UAA.
a) Draw the mRNA transcript that would be made from this DNA molecule.


b) Translate the mRNA and show the amino acid sequence of the encoded protein.


5’-AGGTCCAGTCTTCGGCGGATGATCGGGTCAAACCCGGGGTAACTGGTCACCGGCATCC-3’
3’-TCCAGGTCAGAAGCCGCCTACTAGCCCAGTTTGGGCCCCATTGACCAGTGGCCGTAGG-5’

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Answer #1

1. Explain the difference between spontaneous and induced mutations. Give an example of how each might be caused.

Spontaneous mutation is caused by errors in natural biological processes, whereas induced mutations are mainly man-made and caused by environmental agents.

Spontaneous mutation occurs naturally without human interference. Examples include point mutation.

Induced mutations are set in force by human motivation. People induce mutations via various means like radiation or chemical mutagens.

2. a) Draw the mRNA transcript that would be made from this DNA molecule.

5’-AGGUCCAGUCUUCGGCGGAUGAUCGGGUCAAACCCGGGGUAACUGGUCACCGGCAUCC-3’

b) Translate the mRNA and show the amino acid sequence of the encoded protein.

5'-AUG-AUC-GGG-UCA-AAC-CCG-GGG-UAA-3'

Met-Ile-Gly-Ser-Asn-Pro-Gly

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