It is very important for DNA repair mechanism to be able to recognise the old strand because the new strand should be formed complementary to old strand. It will repair the errors in new strand and correct according to the complementary base pair of old strand.
If this capability are lost then it may repair the old strand as complementary to the new strand instead of vise-versa
9. Why is it important for DNA repair mechanisms to be able to recognize the old...
DNA mismatch repair enzymes preferentially repair bases on the newly synthesized DNA strand, using the old DNA strand as the template. If mismatches were simply repaired without regard for which strand served as template, would this reduce replication errors? Explain your answer (5 pts) Describe DNA replication (remember to mention all the enzymes involved) (10 pts)
Q1: If DNA damage occurred, the cells repair the damage by several mechanisms during the cell cycle. In which phase of the cell cycle cells will repair the damage? Name five of the repair mechanisms that cells are using to repair DNA damage? What are the repair mechanism for double strand DNA breaks? Describe them and Which of them is the error- free repair pathway?
Why is it important to recognize team problems early? What can happen if not addressed? What are five important things a team member must do to be a good team member? How do you repair a stalled team?
10. During repairs the mismatch repair machinery has to distinguish the old DNA strand from the new strand, how does it do this?
Identify the various types of DNA repair mechanisms known to counteract the effects of UV radiation. Recombinational repair Excision repair Photoactivation repair SOS repair 1. is dependent on a photon-activated enzyme that cleaves thymine dimers. 2. is the process by which an endonuclease clips out UV- induced dimers, DNA polymerase III fills in the gap, and DNA ligase rejoins the phosphodiester backbone. 3. uses the corresponding region on the undamaged parental strand of the same polarity. 4. is a process...
A common feature of DNA repair mechanisms is that the lesion (mutated base, adduct, etc) is removed including the sugar phosphate backbone. Give 2 examples of repair mechanism that do that Why is this a common theme? Ie, why does it make sense that all repair mechanisms reach this same point.
Molecular biology of the gene. From the paper “DNA repair mechanisms and the bypass of DNA damage in saccaromyces cerevisiae” 3. In general for methyltransferase a. b. What type of damage does it repair? How does it repair the damage? lanhy the damaged guanine woulr hymine nstead of eyriosine
5. About double strand DNA repair, it is correct to say that choose the most appropriate answer): (a) It requires one intact strand as a template for error correction. (b) Mismatches in the DNA are usually corrected via double strand DNA repair mechanisms. (c) Homologous recombination usually results in DNA repair with no loss of nucleotide at repair site. (d) Non-homologous end-joining usually results in DNA repair with no loss of nucleotide at repair site. 6. A eukaryote gene has two introns and three exons....
1) When DNA is damaged, a cell has a variety of repair pathways available to correct the problem. Discuss their timing, anything they are good at detecting, and explain their specific mechanisms. A) 3pts - Mismatch repair: B) 3pts - Base excision [BER] repair: C) 3pts - Strand breakage repair – compare HRR [homologous recombination repair] and NREJ [non-recombination end joining] 2) 5pts - Discuss how an E. coli origin of replication is recognized [sequences?], opened [by dnaA], and...
Can you please explain in detail heme degradation and explain in detail DNA repair mechanisms. It is really important to me. I will be forever grateful. And if I may ask you one thing if you copy from the internet please put the citations, or links. Thank you in advance!!!