Question

1) a What assumptions are made when using the Hardy– Weinberg formula to estimate genotypic frequencies...

1)

a What assumptions are made when using the Hardy– Weinberg formula to estimate genotypic frequencies from allele frequencies?
b. What are the forces that can change the frequency of an allele in a population?
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Answer #1

Hardy-Weinberg equilibrium:

p+q = 1

p2+2pq+q2 = 1

Conditions for H-W equilibrium:

1. A large population

2. Random mating

3. No natural selection

4. No immigration or emigration

5. No change in allelic frequency due to mutation

Factors that disrupt hardy Weinberg equilibrium:

1. Mutations

2. Natural selection

3. Non-random mating

4. Genetic drift

5. Gene flow

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