How does the poorly hydrolyzable GTP analog GTPS (in which an O atom on the terminal...
How does the poorly hydrolyzable GTP analog GTPS (in which an O atom on the terminal phosphate is replaced with an S atom) affect adenylate cyclase activity? Would it make a difference if Adenylate cyclase was bound by Gia or Gsa?
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How does the poorly hydrolyzable GTP analog GTPS (in which an O
atom on the terminal...
You are conducting an experiment to study epinephrine signaling. You replaced GTP with a poorly hydrolysable...
You are conducting an experiment to study epinephrine signaling. You replaced GTP with a poorly hydrolysable GTP analog (the analog is a compound with a similar structure to GTP that cannot be hydrolyzed to GDP). Which of the following results do you expect: Indicate A or B A.Loss of epinephrine signaling? B. Maintenance or continuation of signaling even in the absence of epinephrine? Which of the following would REVERSE the maintenance or continuation of signaling even in the absence of epinephrine....
GTPY S is a form of GTP that cannot be hydrolyzed to GDP. How would GPCR...
GTPY S is a form of GTP that cannot be hydrolyzed to GDP. How would GPCR signaling through the B 2- adrenergic receptor (epinephrine receptor) be affected in the presence of GTPY S (instead of regular GTP)? CAMP levels would decrease as GTPYS locks the G-protein is in the inactive state. CAMP levels would decrease because GTPYS interferes with epinephrine binding to the receptor. CAMP levels would be similar as with GTP. The phosphorylation state of this nucleotide does not...
18. Which type of bond(s) does O, have when bound to the Fe atom in hemoglobin?...
18. Which type of bond(s) does O, have when bound to the Fe atom in hemoglobin? a. sigma only b. pi only c. sigma and pi d. sigma, pi, and delta 19. Cisplatin works as an anticancer pharmaceutical by... a. sending out NO to kill cancer cells b. binding to DNA so the cancer cells cannot replicate c. sending out reactive oxygen species (ROS), such as peroxides, to kill cancer cells d. decomposing to atomic platinum, which kills the bacteria...
Acetylcholine binds to a GPCR on heart muscle, making the heart beat more slowly. The activated r...
Acetylcholine binds to a GPCR on heart muscle, making the heart beat more slowly. The activated receptor stimulates a G protein, which opens a K channel in the plasma membrane, as shown in the figure below. Which of the following would enhance this effect of the acetylcholine? plasma membrane closed K' channel GTP Pr complex activated α subunit K CHANNEL open K'channel OPENING EXTRACELLULAR SPACE CYTOSOL GTP G-PROTEIN INACTIVATION K" CHANNEL CLOSING closed K' channel rt inactive G protein GOP...
(1) Which one of the following molecules where the central atom does not have an octet?...
(1) Which one of the following molecules where the central atom does not have an octet? (2) Which one of the following molecules where the central atom has more than 8 valence electrons around the central atom? Весі SO HBrO PFS SO3 CHO НАРО SCH BCI, IOCIS IF, XeCl2 Bн, нсіо. (3) Which of the following elements has the largest difference between the first and second ionization energy? A. chlorine B. argon C. potassium D. calcium E.scandium HIO (4) How...
Answer the following question about NH3 A) Difference in state—How does the compound’s use change...
Answer the following question about NH3 A) Difference in state—How does the compound’s use change in a different physical state or when mixed with other compounds at different concentrations? B) Difference in the reactivity of the compound with the reactivity of a similar compound—Does more or less reactivity change the way in which it is used? C) Change in the heat of reaction—Discuss the effects of changing the reaction temperature; for example, would the change make it unsafe, too slow,...
E) [Ar]3d04s44p 2) How many lone pairs of electrons are on the O atom in OF2? A) 0 B) 1 C) 2 D) 3 3) Which atom in...
E) [Ar]3d04s44p 2) How many lone pairs of electrons are on the O atom in OF2? A) 0 B) 1 C) 2 D) 3 3) Which atom in each group (I and II) has the smallest atomic radius? (I) Ca, Ti, Br (II) O, S, Se A) Ca; Se B) Br; Se C) Br; O D) Ca; O 4) How many valence electrons are there in a Bi atom? A) 2 B) 3 C) 4 D) 5 E) 6 5)...
Drosopholia eye development is an example of cell differentiation directed by signal binding to a receptor...
Drosopholia eye development is an example of cell differentiation directed by signal binding to a receptor tyrosine kinase (RTK). In this pathway, R7 photoreceptor development requires a receptor (SEV, sevenless), which is activated by binding to a plasma membrane bound signal (BOSS, bride-of-sevenless) displayed on the adjacent R8 cell Receptor activation leads to activation of RAS via two proteins, Drk (down- stream of receptor kinases) and Sos (son-of-sevenless). Activated RAS leads to activation of a phosphorylation cascade that activates the...
How is compartmentalization achieved in eukaryotic cells? Select one: a. Primarily by membrane-bound structures O b....
How is compartmentalization achieved in eukaryotic cells? Select one: a. Primarily by membrane-bound structures O b. Primarily by endosymbiosis O c. Primarily by cellular structures surrounded by protein O d. Primarily be the cytoskeleton, which divides the cell into different domains for different functions. A mutation to DNA polymerase III that eliminated the 3'-to-5' exonuclease activity would prevent: Select one: O a. removal of the RNA primer. O b.removal of base mismatches. O c. addition of dNTPs to a region...
6. How many unpaired electrons does an atom of phosphorous have in its ground state? (3)...
6. How many unpaired electrons does an atom of phosphorous have in its ground state? (3) 3 (4)5 (1) 1 (2) 2 7. A possible set of quantum numbers for the last electron added to complete an atom of silicon (Si) in its ground state is m eo m, A. 4 0 +% -% В. 3 0 +1 C. 4 1 -1 +% D. 3 1 +1 -% (1) A (2) B (3) C (4) D 8. A possible set...
GTPY S is a form of GTP that cannot be hydrolyzed to GDP. How would GPCR signaling through the B 2- adrenergic receptor (epinephrine receptor) be affected in the presence of GTPY S (instead of regular GTP)? CAMP levels would decrease as GTPYS locks the G-protein is in the inactive state. CAMP levels would decrease because GTPYS interferes with epinephrine binding to the receptor. CAMP levels would be similar as with GTP. The phosphorylation state of this nucleotide does not...
18. Which type of bond(s) does O, have when bound to the Fe atom in hemoglobin? a. sigma only b. pi only c. sigma and pi d. sigma, pi, and delta 19. Cisplatin works as an anticancer pharmaceutical by... a. sending out NO to kill cancer cells b. binding to DNA so the cancer cells cannot replicate c. sending out reactive oxygen species (ROS), such as peroxides, to kill cancer cells d. decomposing to atomic platinum, which kills the bacteria...
Acetylcholine binds to a GPCR on heart muscle, making the heart beat more slowly. The activated receptor stimulates a G protein, which opens a K channel in the plasma membrane, as shown in the figure below. Which of the following would enhance this effect of the acetylcholine? plasma membrane closed K' channel GTP Pr complex activated α subunit K CHANNEL open K'channel OPENING EXTRACELLULAR SPACE CYTOSOL GTP G-PROTEIN INACTIVATION K" CHANNEL CLOSING closed K' channel rt inactive G protein GOP...
(1) Which one of the following molecules where the central atom does not have an octet? (2) Which one of the following molecules where the central atom has more than 8 valence electrons around the central atom? Весі SO HBrO PFS SO3 CHO НАРО SCH BCI, IOCIS IF, XeCl2 Bн, нсіо. (3) Which of the following elements has the largest difference between the first and second ionization energy? A. chlorine B. argon C. potassium D. calcium E.scandium HIO (4) How...
E) [Ar]3d04s44p 2) How many lone pairs of electrons are on the O atom in OF2? A) 0 B) 1 C) 2 D) 3 3) Which atom in each group (I and II) has the smallest atomic radius? (I) Ca, Ti, Br (II) O, S, Se A) Ca; Se B) Br; Se C) Br; O D) Ca; O 4) How many valence electrons are there in a Bi atom? A) 2 B) 3 C) 4 D) 5 E) 6 5)...
Drosopholia eye development is an example of cell differentiation directed by signal binding to a receptor tyrosine kinase (RTK). In this pathway, R7 photoreceptor development requires a receptor (SEV, sevenless), which is activated by binding to a plasma membrane bound signal (BOSS, bride-of-sevenless) displayed on the adjacent R8 cell Receptor activation leads to activation of RAS via two proteins, Drk (down- stream of receptor kinases) and Sos (son-of-sevenless). Activated RAS leads to activation of a phosphorylation cascade that activates the...
How is compartmentalization achieved in eukaryotic cells? Select one: a. Primarily by membrane-bound structures O b. Primarily by endosymbiosis O c. Primarily by cellular structures surrounded by protein O d. Primarily be the cytoskeleton, which divides the cell into different domains for different functions. A mutation to DNA polymerase III that eliminated the 3'-to-5' exonuclease activity would prevent: Select one: O a. removal of the RNA primer. O b.removal of base mismatches. O c. addition of dNTPs to a region...
6. How many unpaired electrons does an atom of phosphorous have in its ground state? (3) 3 (4)5 (1) 1 (2) 2 7. A possible set of quantum numbers for the last electron added to complete an atom of silicon (Si) in its ground state is m eo m, A. 4 0 +% -% В. 3 0 +1 C. 4 1 -1 +% D. 3 1 +1 -% (1) A (2) B (3) C (4) D 8. A possible set...
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