RNA polymerase binds to a promoter with help from a set of proteins called general transcription factors. ... Instead, there is a large class of transcription factors that control the expression of specific, individual genes. For instance, a transcription factor might activate only a set of genes needed in certain neurons.
However, unlike prokaryotic cells, the eukaryotic RNA polymerase requires other proteins, or transcription factors, to facilitate transcription initiation. Transcription factors are proteins that bind to the promoter sequence and other regulatory sequences to control the transcription of the target gene.
Transcription factors are proteins possessing domains that bind to the DNA of promoter or enhancer regions of specific genes. They also possess a domain that interacts with RNA polymerase II or other transcription factors and consequently regulates the amount of messenger RNA (mRNA) produced by the gene.
In eukaryotic cells, there are specific transcription factors (activators) that regulate gene expression. Describe the organization...
Which of the following is not true regarding regulation of gene expression in eukaryotes? In eukaryotic cells, transcriptional activators often work by recruiting the transcriptional macinery to gene promoters DNA methylation is an example of an epigenetic mark that can be inherited Acetylation of histones can result in a more open chromatin structure to allow transcription to occur Different genes can be turned off or on between different organs or stages of development Transcription factor DNA sequences are bound by...
Regulation of Gene Expression in Eukaryotes In all organisms, certain genes are expressed at any given time while other genes are not. Both prokaryotes and eukaryotes regulate gene expression at the transcription stage. However the greater complexity of eukaryotic cells makes it possible for gene expression to be regulated at many other stages as well. The diagram below shows different stages at which gene expression may be regulated in eukaryotes. nucleus chro modifica anscription RNA processing cytoplasm degradation protein processing...
In eukaryotic genomes, regions of _____________________ are transcriptionally active while regions of ____________________ are transcriptionally silent. A) Heterochromatin; euchromatin B) Euchromatin; heterochromatin C) None of the above Which of the following proteins can regulate eukaryotic gene expression WITHOUT binding to the DNA in the regulatory region? A) repressors B) enhancers C) co-activators D) transcription factors In eukaryotes, transcriptional activity can be regulated by methylation of a dinucleotide sequence called "CpG." This modification occurs at a: A) Adenine B) Cytosine C)...
3. Prokaryotic and eukaryotic gene expression compared. Below is an incomplete table of prokaryotic and eukaryotic gene expression in comparison. Fill in the blank using PPT slides, notes and the textbook. Prokaryotic gene expression Eukaryotic gene expression Overview Steps Transcription and translation Yes Transcription and translation coupled? Gene structure No introns Epigenetic modification (chromosome remodeling) transcription, translation, RNA processing, protein processing Transcription in the nucleus and translation in the cytoplasm Interrupted gene with exons and introns RNAPI, II, III Which...
E: For each of the following, indicate whether they regulate eukaryotic gene expression at the transcription level (prior to or during transcription), at the translation level(after transcription/formation of the immature mRNA molecule), or both. 1. Addition of the signal-recognition particle (SRP) 2. DNA methylation 3. Enhancers or insulators
1. trans-acting factors are able to regulate target genes from any chromosome, whereas cis-acting elements can only regulate genes located in the same chromosome. a. True only in operons. In Eukaryotic systems, trans-acting factors only regulate genes in the same chromosome. b. True only in Eukaryotes. Prokaryotes don’t have cis-acting elements. c. True for any organism. d. False. The statement is erroneous 2. Unlike activators, repressors never affect chromatin structure. Repressors inhibit transcription only by binding to the binding sites...
(Multi select) What are the trans acting factors that control transcription in eukaryotic genes? n enhancers. silencers. repressors activators promoters 5 prime end of RNA GU-splice site AG-splice site, TBP stop codon polyadenylation signal
Last week we discussed the role of general transcription factors in forming the transcription initiation complex in eukaryotes. Next week we will look more closely at the regulation of gene expression and the role played by specific transcription factors. Prokaryotes and eukaryotes utilize very different mechanisms for determining which genes are turned on and off and when. In lieu of the prokaryotic operon model, eukaryotes employ a combinatorics approach utilizing both general and specific transcription factors. For this week’s forum,...
Looking at the diagram of transcription in eukaryotes and using the information provided, how could the expression of lactase RNA be turned on and off by transcription factors, activators and repressors? Styles Font Paragraph Activators bind to genes at Rapressors bind to genes seauences and at shaoser sequences and The expression of RNA in eukaryotes is initiated by the binding of basal transcription factors to the promoter sequence of a gene. This leads to the recruitment of RNA polymerase to...
Draw a Eukaryotic Gene Schematic Draw features of importance at the DNA level Transcription start site +1 Promoter - as much detail as you can Gene start ATG and stop codons Transcription Regulatory Sequences such as activators/repressors and enhancers/insulators Draw features of importance at the pre-mRNA level Designate Introns and Exons Designate important Sequences to direct and regulate splicing three important sequences for the chemistry of splicing splicing regulatory sequences (ISS, ISE, ESE, ESS) Modifications at level of pre-mRNA UTRs,...