1. Draw a synteny plot of two genomes that have the following gene arrangements: a. Genome 1: ori...
1. Draw a synteny plot of two genomes that have the following gene arrangements:
a. Genome 1: origin-A-B-C-D-E
Genome 2: origin-A-B-non-coding intervening sequence-C-D-D-E
b. Genome 1: origin-A-B-C-D-E
Genome 2: origin-A-B-D-C-E. Note that in Genome 2 there is an inversion.
c. Genome 1: origin-A-B-C-D-A
Genome 2: origin-A-B-C-D-A
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1. Draw a synteny plot of two genomes that have the following gene arrangements: a. Genome 1: ori...
You identify a gene (gene 1) in once species (species 1) that shares significant homology to...
You identify a gene (gene 1) in once species (species 1) that shares significant homology to a gene (gene 2) in a second species (species 2). Species 1 and species 2 share a common ancestor. Gene 1 and Gene 2 lie within in blocks of sequences that show synteny between the two species. You determine the number and identity of synonymous and non-synonymous sequence changes in the coding sequences when comparing the two genes. From these data alone (i.e., without...
A-E please 10. You inherit a sequencing machine and decide to sequence the genome of an...
A-E please
10. You inherit a sequencing machine and decide to sequence the genome of an animal. A. (2pts) What animal would you pick? Briefly explain why. B. (6pts) How would you find the protein-coding genes in a new genome sequence? Describe one computational method and one experimental method. C. (4pts) List 4 other DNA elements would you expect to find in a new genome in addition to protein-coding genes? D. (3pts) If you compared the chromosomal organization of dogs,...
Given the following diagram of a typical eukaryotic coding gene, draw a basic sketch showing gene...
Given the following diagram of a typical eukaryotic coding gene, draw a basic sketch showing gene transcription and processing into a mature mRNA. a. Given your answer to question 1, would you expect a typical mRNA (or its derived cDNA) sequence to completely align with a genomic sequence in a single contiguous location? (i.e., the mRNA sequence aligns without breaks to the genomic sequence)? Explain. Why is it easier to predict the location of genes in microbial genomes than in...
1. True or False: Different cells in an individual’s body have different genomes 2. Which of...
1. True or False: Different cells in an individual’s body have different genomes 2. Which of the following describes a genome-wide association study? A) A study that sequenced the genome of an aggressive metastatic breast cancer biopsy from a 22-year-old patient to determine the genetic mutations present B) A study that treated adult somatic cells with a transcription factor to understand how that transcription factor changes gene expression and the cellular phenotype C) A California study that sequenced the CFTR...
estion 18 and Two-dimensional gel electrophoresis separates proteins based on a. size; shape b.shape; charge C....
estion 18 and Two-dimensional gel electrophoresis separates proteins based on a. size; shape b.shape; charge C. size; concentration d. size; charge e concentration; shape Question 14 When eukaryotic genomes and prokaryotic genomes are compared, a. in eukaryotic genomes, there is a single origin of replication on each chromosome. b.eukaryotic genomes tend to have fewer regulatory sequences than prokaryotic genomes. c. the percentage of the genome devoted to coding sequences in eukaryotic genomes is lower than in prokaryotic genomes. d. eukaryotic...
1 What is an imprinted gene? Select one: a. A gene that is found on a...
1 What is an imprinted gene? Select one: a. A gene that is found on a Barr body b. A gene that is silenced upon inheritance from a designated parent c. A gene that is inherited from only one parent d. A gene that is encoded on only one of the two copies of a chromosome Question 2 Which of the following is NOT a typical characteristic of cancer? Select one: a. Malignant cancers are typically not able to metastasize...
1) You have two human liver cells (A and B) and you hypothesize that the insulin...
1) You have two human liver cells (A and B) and you hypothesize that the insulin receptor gene in Cell A has a mutation in exon 1 and Cell B contains the wild type sequence. You extract genomic DNA from each of the cells. Of the following, what would be the most efficient (quick, precise and relatively cheap) way to test your hypothesis. a. Isolate protein from both cells, purify the insulin receptor, and determine the amino acid content. b. Sequence the...
Question 12 12 points A doctor acquires genomic information from her patient. After examining the patient's...
Question 12 12 points A doctor acquires genomic information from her patient. After examining the patient's sequence and inferring risk factors, she tells her patient that he has an elevated risk of acquiring prostate cancer and recommends an aggressive course of screening. This example characterizes a. pharmacogenomics b. metagenomics functional genomics d. personal genomics e comparative genomics. Question 14 When eukaryotic genomes and prokaryotic genomes are compared, a. in eukaryotic genomes, there is a single origin of replication on each...
Question 7 estion 7 0.3125 points Suppose that in a Sanger sequencing reaction, sequences are readable...
Question 7 estion 7 0.3125 points Suppose that in a Sanger sequencing reaction, sequences are readable for a few dozen nucleotides but then become increasingly difficult to road. It is determined that the chains are terminated to readily. What is the most likely cause? a. Too much of the dNTPs b. Insufficient fluorescent dye Too much fluorescent dye d. Incorrect primer e. Insufficient dNTPs Question of 20 Moving to another question will save this response Question 13 Which statement comparing...
which one of the following is not characteristic of prokaryotic genomes? a may have have histone...
which one of the following is not characteristic of prokaryotic genomes? a may have have histone like proteins associated in chromatin b) presence of introns c) gene rearranged in operons d) presence of exons e) distinct replication site
A-E please
10. You inherit a sequencing machine and decide to sequence the genome of an animal. A. (2pts) What animal would you pick? Briefly explain why. B. (6pts) How would you find the protein-coding genes in a new genome sequence? Describe one computational method and one experimental method. C. (4pts) List 4 other DNA elements would you expect to find in a new genome in addition to protein-coding genes? D. (3pts) If you compared the chromosomal organization of dogs,...
Given the following diagram of a typical eukaryotic coding gene, draw a basic sketch showing gene transcription and processing into a mature mRNA. a. Given your answer to question 1, would you expect a typical mRNA (or its derived cDNA) sequence to completely align with a genomic sequence in a single contiguous location? (i.e., the mRNA sequence aligns without breaks to the genomic sequence)? Explain. Why is it easier to predict the location of genes in microbial genomes than in...
estion 18 and Two-dimensional gel electrophoresis separates proteins based on a. size; shape b.shape; charge C. size; concentration d. size; charge e concentration; shape Question 14 When eukaryotic genomes and prokaryotic genomes are compared, a. in eukaryotic genomes, there is a single origin of replication on each chromosome. b.eukaryotic genomes tend to have fewer regulatory sequences than prokaryotic genomes. c. the percentage of the genome devoted to coding sequences in eukaryotic genomes is lower than in prokaryotic genomes. d. eukaryotic...
Question 12 12 points A doctor acquires genomic information from her patient. After examining the patient's sequence and inferring risk factors, she tells her patient that he has an elevated risk of acquiring prostate cancer and recommends an aggressive course of screening. This example characterizes a. pharmacogenomics b. metagenomics functional genomics d. personal genomics e comparative genomics. Question 14 When eukaryotic genomes and prokaryotic genomes are compared, a. in eukaryotic genomes, there is a single origin of replication on each...
Question 7 estion 7 0.3125 points Suppose that in a Sanger sequencing reaction, sequences are readable for a few dozen nucleotides but then become increasingly difficult to road. It is determined that the chains are terminated to readily. What is the most likely cause? a. Too much of the dNTPs b. Insufficient fluorescent dye Too much fluorescent dye d. Incorrect primer e. Insufficient dNTPs Question of 20 Moving to another question will save this response Question 13 Which statement comparing...
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